550377-89-4

Basic information

• Product Name: 4-{[tert-butyl(dimethyl)silyl]oxy}-2-chlorobenzaldehyde
• Synonyms: 4-{[tert-butyl(dimethyl)silyl]oxy}-2-chlorobenzaldehyde
• CAS NO: 550377-89-4
• Molecular Weight: 270.831
• Mol File: 550377-89-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 4-{[tert-butyl(dimethyl)silyl]oxy}-2-chlorobenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{[tert-butyl(dimethyl)silyl]oxy}-2-chlorobenzaldehyde(550377-89-4)
• EPA Substance Registry System: 4-{[tert-butyl(dimethyl)silyl]oxy}-2-chlorobenzaldehyde(550377-89-4)

Safety Data

• Hazardous Substances Data: 550377-89-4(Hazardous Substances Data)

Upstream product

• 108-43-0 3-monochlorophenol 
• 56962-11-9 2-chloro-4-hydroxybenzaldehyde 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 1169947-65-2 C₁₆H₁₃ClO₃ 
• 959801-07-1 3-(2-{2-chloro-4-[3-(2,6-dichloro-phenyl)-5-isopropyl-3H-[1,2,3]triazol-4-ylmethoxy]-phenyl}-vinyl)-benzoic acid methyl ester 

Relevant articles and documents

OPIOID RECEPTOR MODULATORS AND PRODUCTS AND METHODS RELATED THERETO

Compounds are provided having the structure of Formula (I): or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein A, B, L, R3, R4, R5, R6, R8, m and n are as defined herein. Such compounds modulate the opioid receptor, particulare the mu-opioid receptor (MOR) and/or the kappa-opioid receptor (KOR), and/or the delta-opioid receptor (DOR). Products containing such compounds, as well as methods for their use and preparation, are also provided.

NOVEL FXR (NR1H4 ) BINDING AND ACTIVITY MODULATING COMPOUNDS

The present invention relates to compounds which bind to the NR1 H4 receptor (FXR) and act as agonists of the NR1 H4 receptor (FXR). The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds, and to a process for the synthesis of said compounds.

Novel method for synthesizing spiro[4.5]cyclohexadienones through a Pd-catalyzed intramolecular ipso-Friedel-Crafts allylic alkylation of phenols

The first successful Pd-catalyzed intramolecular ipso-Friedel-Crafts allylic alkylation of phenols, which provided a new access to spiro[4.5]cyclohexadienones, is described. The present method could be applied to catalytic enantioselective construction of