55052-26-1

Basic information

• Product Name: 6H-Pyrrolo[2,3-b]pyridin-6-one, 1,7-dihydro-
• Synonyms: 6H-Pyrrolo[2,3-b]pyridin-6-one, 1,7-dihydro-;1H-Pyrrolo[2,3-b]pyridin-6-ol;1,7-dihydro-6H-Pyrrolo[2,3-b]pyridin-6-one;6H-Pyrrolo[2,3-b]pyridin-6-one;1H-pyrrolo[2,3-b]pyridin-6(7H)-one
• CAS NO: 55052-26-1
• Molecular Formula: C7H6N2O
• Molecular Weight: 134.14
• Mol File: 55052-26-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 226-226.5℃ (decomposition)
• Boiling Point: 444.608°C at 760 mmHg
• Flash Point: 222.691°C
• Appearance: /
• Density: 1.336g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.635
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 6H-Pyrrolo[2,3-b]pyridin-6-one, 1,7-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 6H-Pyrrolo[2,3-b]pyridin-6-one, 1,7-dihydro-(55052-26-1)
• EPA Substance Registry System: 6H-Pyrrolo[2,3-b]pyridin-6-one, 1,7-dihydro-(55052-26-1)

Safety Data

• Hazardous Substances Data: 55052-26-1(Hazardous Substances Data)

Usage

General Description

6H-Pyrrolo[2,3-b]pyridin-6-one, 1,7-dihydro- is a chemical compound that belongs to the class of heterocyclic compounds. It is a derivative of pyridine and contains a pyrrolidine ring fused to a pyridine ring. 6H-Pyrrolo[2,3-b]pyridin-6-one, 1,7-dihydro- is used in the pharmaceutical industry as a building block for the synthesis of various bioactive molecules and drugs. Its structure and reactivity make it a valuable intermediate in organic synthesis, particularly in the development of new pharmaceuticals. Additionally, it has potential applications in the field of materials science and as a research tool in chemical biology.

InChI:InChI=1/C7H6N2O/c10-6-2-1-5-3-4-8-7(5)9-6/h1-4H,(H2,8,9,10)

Upstream product

• 111293-49-3 6-acetoxy-1-acetyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine 
• 10592-27-5 7-azaindoline 
• 114402-41-4 2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-7-oxide 
• 99068-42-5 2,3-dihydro-pyrrolo[2,3-b]pyridine-1-carboxylic acid ethyl ester 
• 55052-25-0 1-acetyl-1H-pyrrolo[2,3-b]pyridin-6-yl acetate 

Downstream Products

• 896722-53-5 6-methoxy-1H-pyrrolo[2,3-b]pyridine 

Relevant articles and documents

AZAINDOLE CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS

Provided herein are compounds of Formula (I) and Formula (II): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of tuberculosis.

Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents

Utilizing scaffold-hopping drug-design strategy, we sought to identify a backup drug candidate for BPR0L075 (1), an indole-based anticancer agent. For this purpose, 5,6-fused bicyclic heteroaromatic scaffolds were designed and synthesized through shufflin