55084-15-6

Basic information

• Product Name: 2-(BIS-METHYLSULFANYL-METHYLENE)-MALONIC ACID DIETHYL ESTER
• Synonyms: 2-(BIS-METHYLSULFANYL-METHYLENE)-MALONIC ACID DIETHYL ESTER
• CAS NO: 55084-15-6
• Molecular Formula: C₁₀H₁₆O₄S₂
• Molecular Weight: 264.36164
• Mol File: 55084-15-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 323°C at 760 mmHg
• Flash Point: 142.9°C
• Appearance: /
• Density: 1.192g/cm³
• Vapor Pressure: 0.000269mmHg at 25°C
• Refractive Index: 1.522
• CAS DataBase Reference: 2-(BIS-METHYLSULFANYL-METHYLENE)-MALONIC ACID DIETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(BIS-METHYLSULFANYL-METHYLENE)-MALONIC ACID DIETHYL ESTER(55084-15-6)
• EPA Substance Registry System: 2-(BIS-METHYLSULFANYL-METHYLENE)-MALONIC ACID DIETHYL ESTER(55084-15-6)

Safety Data

• Hazardous Substances Data: 55084-15-6(Hazardous Substances Data)

Usage

General Description

2-(Bis-methylsulfanyl-methylene)-malonic acid diethyl ester is a chemical compound with the molecular formula C10H18O6S2. It is a diethyl ester derivative of malonic acid, and it contains a bis-methylsulfanyl-methylene group. 2-(BIS-METHYLSULFANYL-METHYLENE)-MALONIC ACID DIETHYL ESTER is used in organic synthesis as a reagent for the preparation of various organic compounds. It has potential applications in pharmaceuticals, agrochemicals, and materials science due to its versatile chemical properties. It is a colorless to pale yellow liquid with a characteristic odor, and it should be handled and stored in accordance with safe chemical handling practices.

InChI:InChI=1/C10H16O4S2/c1-5-13-8(11)7(9(12)14-6-2)10(15-3)16-4/h5-6H2,1-4H3

Upstream product

• 75-15-0 carbon disulfide 
• 105-53-3 diethyl malonate 
• 74-88-4 methyl iodide 
• 74-83-9 methyl bromide 

Downstream Products

• 759-24-0 tert-butylmalonic acid diethyl ester 
• 60140-47-8 2-(1-Benzyl-2-phenyl-ethylidene)-malonic acid 
• 153391-45-8 6-(4-Chloro-phenyl)-4-methylsulfanyl-2-oxo-2H-pyran-3-carboxylic acid ethyl ester 
• 19672-33-4 trityl-malonic acid diethyl ester 
• 812692-25-4 ethyl 1-(4-fluorophenyl)-4-(methylthio)-2-[4-(methylthio)phenyl]-6-oxo-1,6-dihydropyrimidine-5-carboxylate 
• 1259434-10-0 ethyl 3-ethoxy-5-(methylthio)-1-phenyl-1H-pyrazole-4-carboxylate 

Relevant articles and documents

Tin tetrachloride-catalyzed regiospecific allylic substitution of quinone monoketals: An easy entry to benzofurans and coumestans

A highly regioselective allylic substitution of quinone monoketals with a-oxoketene dithioacetals is achieved under the catalysis of only tin tetrachloride (1 mol%). The advantages of the reaction, including its simplicity, rapidity, low catalyst loading of inexpensive tin tetrachloride, mild conditions and; in particular, the regiospecificity, is proposed to be due to a pseudo-intramolecular process. This new synthetic method provides a facile [3+2] cycloaddition route to benzofurans and is highlighted by the synthesis of coumestans.

Synthesis of substituted isoxazoles and pyrazoles from α-α Dioxoketen dithioacetals under solvothermal conditions

Some new 3,4,5-substituted isoxazoles, 3,4,5 and 1,3,4,5-substituted pyrazoles were prepared by reaction of,-oxoketen dithioacetals with hydroxylamine hydrochloride; phenyl hydrazine and hydrazine hydrate respectively under solvothermal conditions involving an ecofriendly method without any environmental pollution. The yields are in the range of 71-91%. The structure of the new compounds were established upon their elemental analysis, IR, 1H NMR, and 13C NMR. Copyright Taylor & Francis Group, LLC.

A convenient one-pot synthesis of ketene dithioacetals

An easy synthesis of ketene dithioacetals 2 and 3 by the condensation of carbon disulfide and active methylene compounds 1 with subsequent alkylation in the presence of potassium fluoride is described.