551-33-7Relevant articles and documents
Reconstitution of Apomyoglobin with Bile Pigments
Falk, Heinz,Marko, Helmut,Mueller, Norbert,Schmitzberger, Wolfgang,Stumpe, Hugo
, p. 893 - 901 (1990)
Apomyoglobin was reconstituted with bile pigments of the verdinoid, 2,3-dihydroverdinoid, pterobilinoid, and violinoid type.Absorption and circular dichroism data as well as formation constants of the complexes were measured.From these results it was concluded that chromophore binding and induced chirality of these pigments are mainly governed by a lipophilic region opposite to the propionic side chain(s) and the asymmetric position of the hydrogen bonding acceptors of the propionic acid side chain(s) at the entrance of the protein pocket.
Synthesis of Unsymmetric Bile Pigments: Mesobilirubin-VIIIα, 17-Desvinyl-17-ethyl-bilirubin-VIIIα and 12-Despropionic Acid-12-ethyl-mesobilirubin-XIIIα
Trull, Francesc R.,Lightner, David A.
, p. 1227 - 1230 (2007/10/02)
The unnatural bile pigments 17-desvinyl-17-ethylbilirubin-VIIIα, mesobilirubin-VIIIα and 12-despropionic acid-12-ethyl mesobilirubin-XIIIα were synthesized via (1) "reverse scrambling" of bilirubin-XIIIα or mesobilirubin-IXα with mesobilirubin-IVα or etiobilirubin-IVγ or (2) following coupling of xanthobilirubic acid methyl ester with ψ-xanthobilirubic acid methyl ester, or coupling of xanthobilirubic acid methyl ester with kryptopyrromethenone.