55150-07-7

Basic information

• Product Name: Methyl 5-chloro-2-(methylamino)benzoate
• Synonyms: Methyl 5-chloro-2-(methylamino)benzoate;methyl N-methyl-5-chloro-anthranilate
• CAS NO: 55150-07-7
• Molecular Formula: C₉H₁₀ClNO₂
• Molecular Weight: 199.6342
• Mol File: 55150-07-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 63-64 °C
• Boiling Point: 307.8±22.0 °C(Predicted)
• Appearance: /
• Density: 1.257±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 2.11±0.12(Predicted)
• CAS DataBase Reference: Methyl 5-chloro-2-(methylamino)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 5-chloro-2-(methylamino)benzoate(55150-07-7)
• EPA Substance Registry System: Methyl 5-chloro-2-(methylamino)benzoate(55150-07-7)

Safety Data

• Hazardous Substances Data: 55150-07-7(Hazardous Substances Data)

Usage

General Description

Methyl 5-chloro-2-(methylamino)benzoate is a chemical compound used in the production of pharmaceuticals and agrochemicals. It is an ester, meaning it is formed from the reaction of an organic acid and an alcohol. Methyl 5-chloro-2-(methylamino)benzoate is commonly used as an intermediate in the synthesis of various medications and pesticides. Its chemical structure consists of a benzoate group with a chlorine atom and a methylamino group attached to it, making it a versatile building block for the synthesis of a wide range of organic compounds. Methyl 5-chloro-2-(methylamino)benzoate is a valuable chemical for the pharmaceutical and agricultural industries due to its versatile usage in the synthesis of various important products.

Upstream product

• 521064-80-2 5-chloro-2-dimethylaminobenzoic acid methyl ester 
• 134-20-3 2-carbomethoxyaniline 
• 635-21-2 5-chloroanthranilic acid 

Downstream Products

• 889849-90-5 5-Chloro-2-[(2-cyano-acetyl)-methyl-amino]-benzoic acid methyl ester 
• 67447-29-4 2'-N-Methylamino-5'-chloro-2-(phenylsulphonyl)-acetophenone 
• 33280-14-7 5-chloro-2-methylamino-benzoic acid 
• 10320-59-9 1-methyl-6-chloroquinazolin-2,4-dione 

Relevant articles and documents

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Inspired by the natural product evodiamine, a novel antitumor indolopyrazinoquinazolinone scaffold was designed by scaffold hopping. Structure-activity relationship studies led to the discovery of compound 15j, which shows low nanomolar inhibitory activity against the HCT116 cell line. Further antitumor mechanism studies indicated that compound 15j acted by the dual inhibition of topoisomerase 1 and tubulin and induced apoptosis with G2 cell-cycle arrest. The quaternary ammonium salt of compound 15j (compound 15js) exhibited excellent in vivo antitumor activity (TGI = 66.6%) in the HCT116 xenograft model with low toxicity. Indolopyrazinoquinazolinone derivatives represent promising multitargeting antitumor leads for the development of novel antitumor agents.

Aryl triazines as LPAAT-SS inhibitors and uses thereof

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