55179-20-9

Basic information

• Product Name: 2-[4-(4-chlorophenyl)piperazin-1-yl]ethanol
• CAS NO: 55179-20-9
• Molecular Formula: C₁₂H₁₇ClN₂O
• Molecular Weight: 240.7292
• Mol File: 55179-20-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 397.2°C at 760 mmHg
• Flash Point: 194°C
• Density: 1.204g/cm³
• Vapor Pressure: 5.05E-07mmHg at 25°C
• Refractive Index: 1.572
• CAS DataBase Reference: 2-[4-(4-chlorophenyl)piperazin-1-yl]ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(4-chlorophenyl)piperazin-1-yl]ethanol(55179-20-9)
• EPA Substance Registry System: 2-[4-(4-chlorophenyl)piperazin-1-yl]ethanol(55179-20-9)

Safety Data

• Hazardous Substances Data: 55179-20-9(Hazardous Substances Data)

Usage

Chemical compound

2-[4-(4-chlorophenyl)piperazin-1-yl]ethanol

Classification

Piperazine derivative

Properties

Psychoactive drug, selective serotonin receptor agonist

Uses

Scientific research to study effects of serotonin on the brain, precursor in synthesis of other chemicals

Pharmacological properties

Potential antidepressant and anxiolytic effects

Caution

Potential health risks and side effects, handle with care

Upstream product

• 75-21-8 oxirane 
• 38212-33-8 4-(4-chlorophenyl) piperazine 
• 106-47-8 4-chloro-aniline 
• 540-51-2 2-bromoethanol 

Downstream Products

• 89841-33-8 1-(p-Chlorophenyl)-4-<2-(trimethylsiloxy)ethyl>piperazine 
• 90095-99-1 2-[4-(4-chlorophenyl)-1-piperazinyl]ethyl methyl 4-(3-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 90095-95-7 2-[4-(4-chlorophenyl)-1-piperazinyl]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 
• 1262048-26-9 2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl methanesulfonate 

Relevant articles and documents

Spiro[pyrrolidine-3,3′-oxindoles] as 5-HT7 receptor ligands

Here we report the design and synthesis of spiro[pyrrolidine-3,3′-oxindole] derivatives representing a novel scaffold of 5-HT7 receptor ligands. The synthesized analogues were validated as low nanomolar ligands showing selectivity in a panel of

Synthesis of a novel series of 4-arylpiperazinyl derivatives linked to a 2-(Pyridin-3-yl)-1H-benzimidazole as new delavirdine analogues

The synthesis of a series of substituted arylpiperazines linked to a 2-(pyridin-3-yl)-1H-benzo[d] imidazole scaffold through an alkylic linker is reported. The novel 1-(2-(4-arylpiperazin-1-yl) alkyl)-2-(pyridin-3-yl)-1H- benzimidazole derivatives are structurally related to the anti-HIV-1 drug Delavirdine and belong to the bis(heteroaryl)piperazines family (BHAPs), a well known HIV-1 reverse transcriptase inhibitors group.