55182-63-3

Basic information

• Product Name: 4‐(2‐hydroxypropan‐2‐yl)‐2,6‐dimethylphenol
• Synonyms: 4‐(2‐hydroxypropan‐2‐yl)‐2,6‐dimethylphenol
• CAS NO: 55182-63-3
• Molecular Weight: 180.247
• Mol File: 55182-63-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4‐(2‐hydroxypropan‐2‐yl)‐2,6‐dimethylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4‐(2‐hydroxypropan‐2‐yl)‐2,6‐dimethylphenol(55182-63-3)
• EPA Substance Registry System: 4‐(2‐hydroxypropan‐2‐yl)‐2,6‐dimethylphenol(55182-63-3)

Safety Data

• Hazardous Substances Data: 55182-63-3(Hazardous Substances Data)

Upstream product

• 2374-05-2 4-bromo-2,6-dimethyl-phenol 
• 67-64-1 acetone 
• 5325-04-2 1-(4-hydroxy-3,5-dimethylphenyl)ethanone 
• 75-16-1 methylmagnesium bromide 
• 917-64-6 methyl magnesium iodide 
• 34137-14-9 methyl 4-hydroxy-3,5-dimethylbenzoate 

Downstream Products

• 10569-71-8 4‐i‐propyl‐2,6‐dimethylphenol 
• 55182-49-5 4-Isopropyliden-2,6-dimethyl-2,5-cyclohexadienon 
• 32565-73-4 1-(3,5-dimethyl-4-hydroxyphenyl)-6-hydroxy-1,3,3,5,7-pentamethyl-1,2-dihydroindene 

Relevant articles and documents

Site-selective Oxidative Dearomatization of Phenols and Naphthols into ortho-Quinols or Epoxy ortho-Quinols using Oxone as the Source of Dimethyldioxirane

A novel reactivity of dimethyldioxirane, generated in situ from Oxone and acetone, with substituted phenols and naphthols is reported. This methodology allowed the synthesis of ortho-quinols or epoxy ortho-quinols from a site-selective oxidative dearomatization process, with good yields under very mild conditions. A short total synthesis of natural product lacinilene C methyl ether is also described using this process as the key step. (Figure presented.).