55198-39-5

Basic information

• Product Name: Benzoic acid, 2-amino-, octyl ester
• CAS NO: 55198-39-5
• Molecular Formula: C15H23NO2
• Molecular Weight: 249.353
• Mol File: 55198-39-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-amino-, octyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-amino-, octyl ester(55198-39-5)
• EPA Substance Registry System: Benzoic acid, 2-amino-, octyl ester(55198-39-5)

Safety Data

• Hazardous Substances Data: 55198-39-5(Hazardous Substances Data)

Upstream product

• 111-83-1 1-bromo-octane 
• 37960-65-9 potassium anthranilate 
• 111-87-5 octanol 
• 118-92-3 anthranilic acid 
• 134-20-3 2-carbomethoxyaniline 
• 118-48-9 isatoic anhydride 

Downstream Products

• 1415326-11-2 C₁₅H₂₁N₃O₂ 
• 101689-32-1 2-(4-Hydroxy-3,6-dioxo-5-undecyl-cyclohexa-1,4-dienylamino)-benzoic acid octyl ester 

Relevant articles and documents

Synthesis and cytotoxicity of some d-mannose click conjugates with aminobenzoic acid derivatives

Two sets of new conjugates obtained from d-mannose derivatives and o-, m-, and p-substituted benzoic acid esters interconnected through a triazole ring were synthesized by Cu(I) catalyzed azide-alkyne cycloaddition. All synthesized compounds were tested for their in vitro cytotoxic activity against seven cancer cell lines with/without multidrug resistance phenotype as well as non-tumor MRC-5 and BJ fibroblasts. Butyl ester of 4-aminobenzoic acid 6c showed the highest activity among all tested compounds, however, it was active only against K562 myeloid leukemia cells. N-Glycosyltriazole conjugates, both acetylated and nonacetylated at mannose moiety, were almost completely inactive. In contrast, some of the acetylated O-glycosyl conjugates showed cytotoxic activity which was cell line dependent and strongly affected by position of benzoic acid substitution as well as a length of its ester alkyl chain; the most potent compound was acetylated mannoside conjugated with octyl ester of m-substituted benzoic acid. However, deacetylation resulting in hydrophilicity increase of the glycosides almost completely abolished their cytotoxic potency.

CONVENIENT SYNTHESIS OF ESTERS OF 2-PYRROLECARBOXYLIC ACID AND OF PYRIDINECARBOXYLIC ACIDS BY SOLID-LIQUID PHASE TRANSFER CATALYSIS WITHOUT ADDED SOLVENT

By reaction of aromatic K-carboxylates having nucleophilic N-atom in solid-liquid phase transfer catalysis (PTC) conditions without added solvent (catalyst : tetraalkylammonium halide) with alkylating reagents, the corresponding esters are prepared.By a judicious choice of experimental conditions, the amounts of N-alkylated products can be lowered.From 2-pyrrolecarboxylic acid, the three isomers of pyridinecarboxylic acid and o-aminobenzoic acid, corresponding esters of ethyl, benzyl, n-octyl and n-cetyl, generally are obtained with good yields.