5520-22-9

Basic information

• Product Name: 2-(4-phenylbutyl)pyridine
• Synonyms: 2-(4-phenylbutyl)pyridine
• CAS NO: 5520-22-9
• Molecular Formula: C₁₅H₁₇N
• Molecular Weight: 211.3
• Mol File: 5520-22-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 324.7°Cat760mmHg
• Flash Point: 136.3°C
• Appearance: /
• Density: 1.01g/cm³
• Vapor Pressure: 0.000456mmHg at 25°C
• Refractive Index: 1.56
• CAS DataBase Reference: 2-(4-phenylbutyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-phenylbutyl)pyridine(5520-22-9)
• EPA Substance Registry System: 2-(4-phenylbutyl)pyridine(5520-22-9)

Safety Data

• Hazardous Substances Data: 5520-22-9(Hazardous Substances Data)

Usage

General Description

2-(4-phenylbutyl)pyridine is a chemical compound with the molecular formula C18H20N. It is a pyridine derivative that contains a phenylbutyl group attached to the nitrogen atom. 2-(4-phenylbutyl)pyridine is often used as a ligand in coordination chemistry and catalysis. It has been studied for its potential applications in organic synthesis and medicinal chemistry. Additionally, 2-(4-phenylbutyl)pyridine is known for its aromatic and sweet odor. Due to its structural properties, it may have various industrial and scientific uses.

InChI:InChI=1/C15H17N/c1-2-8-14(9-3-1)10-4-5-11-15-12-6-7-13-16-15/h1-3,6-9,12-13H,4-5,10-11H2

Upstream product

• 109-06-8 α-picoline 
• 104-52-9 phenylpropyl chloride 
• 15295-69-9 hept-6-ynenitrile 
• 74-86-2 acetylene 
• 1121-60-4 pyridine-2-carbaldehyde 
• 1462-75-5 3-phenylpropylmagnesium bromide 
• 2294-75-9 2-(3-butenyl)pyridine 
• 98-80-6 phenylboronic acid 
• 100-69-6 2-vinylpyridine 
• 34420-17-2 (2-phenylethyl)boronic acid 

Relevant articles and documents

Unlocking the Accessibility of Alkyl Radicals from Boronic Acids through Solvent-Assisted Organophotoredox Activation

Despite their prevalence in organic synthesis, the application of boronic acids (BAs) as alkyl radical precursors in visible-light-assisted photocatalyzed reactions has been limited by their high oxidation potential. This study demonstrates the prominent

Nickel-Catalyzed Hydrogenolysis and Conjugate Addition of 2-(Hydroxymethyl)pyridines via Organozinc Intermediates

2-Hydroxymethylpyridines undergo nickel-catalyzed hydrogenolysis upon activation with a chlorophosphate. Reactions employ diethylzinc and are proposed to proceed through secondary benzylzinc reagents. Quenching with deuteromethanol provides straightforward incorporation of a deuterium label in the benzylic position. Intramolecular conjugate additions with α,β-unsaturated esters are also demonstrated and support the intermediacy of a benzylzinc complex.