552293-34-2 Usage
General Description
Intermediate of Rolapitant is a chemical compound that serves as an intermediate in the production of Rolapitant, which is a substance used in the treatment of chemotherapy-induced nausea and vomiting. This intermediate compound is synthesized through a series of chemical reactions and serves as a crucial building block in the synthesis of Rolapitant. It plays a key role in the overall manufacturing process of this important pharmaceutical compound, and is an essential component in ensuring the production of high-quality Rolapitant for use in medical treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 552293-34-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,2,2,9 and 3 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 552293-34:
(8*5)+(7*5)+(6*2)+(5*2)+(4*9)+(3*3)+(2*3)+(1*4)=152
152 % 10 = 2
So 552293-34-2 is a valid CAS Registry Number.
552293-34-2Relevant articles and documents
And as the antagonist aminopyrrolidine deriv. NK1 aminopiperidine (by machine translation)
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, (2016/10/08)
A NK 1 antagonist having the formula (I), wherein Ar 1 and Ar 2 are optionally substituted phenyl or heteroaryl, X 1 is an ether, thio or imino linkage, R 4 and R 5 are not both H or alkyl, and the remaining variables are as defined in the specification, useful for treating a number of disorders, including emesis, depression, anxiety and cough. Pharmaceutical compositions. Methods of treatment and combinations with other agents are also disclosed.
FUSED RING NK1 ANTAGONISTS
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Page/Page column 57, (2008/06/13)
A compound having the general structure shown in Formula (1) or pharmaceutically acceptable salts and/or solvates thereof are useful in treating diseases or conditions mediated by NK1 receptors, for example various physiological disorders, symptoms or dis
