5523-19-3 Usage
Description
Boron trichloride-methyl sulfide complex is a chemical compound that combines boron trichloride (BCl3) with methyl sulfide (CH3SH). This complex is known for its convenience as a solid form of boron trichloride, which is typically a gas at room temperature. The combination with methyl sulfide provides a more stable and easily handled form of the reagent.
Uses
Used in Organic Chemistry:
Boron trichloride-methyl sulfide complex is used as a convenient reagent for the dealkylation of aryl ethers. Its solid form allows for easier handling and storage compared to the gaseous boron trichloride, making it a preferred choice in various chemical reactions and synthesis processes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, the complex may be utilized in the synthesis of various drugs and drug intermediates, taking advantage of its dealkylation properties to create specific molecular structures required for drug development.
Used in Chemical Research:
Boron trichloride-methyl sulfide complex can be employed in academic and industrial research settings to study the reactivity of aryl ethers and other related compounds. Its solid form facilitates controlled experiments and the exploration of new reaction pathways.
Check Digit Verification of cas no
The CAS Registry Mumber 5523-19-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,2 and 3 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5523-19:
(6*5)+(5*5)+(4*2)+(3*3)+(2*1)+(1*9)=83
83 % 10 = 3
So 5523-19-3 is a valid CAS Registry Number.
InChI:InChI=1/C2H6BCl3S/c1-7(2)3(4,5)6/h1-2H3
5523-19-3Relevant articles and documents
Diethyl(di-tert-butylphosphino)borane and related compounds: The first stable monomeric tetraalkyl phosphinoborane
Groshens, Thomas J.,Higa, Kelvin T.,Nissan, Robin,Butcher, Raymond J.,Freyer, Alan J.
, p. 2904 - 2910 (2008/10/08)
Four new phosphinoborane compounds were prepared and characterized by 1H, 13C, 31P, and 11B NMR spectroscopy and elemental analysis. Monomeric Et2BP(t-Bu)2 was isolated as a volatile yellow liquid and [Me2BP(t-Bu)2]2 as a colorless solid using salt elimination reactions. The colorless dimeric solids [Me2BP(SiMe3)2]2 and [Et2BP(SiMe3)2]2 were prepared via trimethylsilyl halide elimination reactions. The dimeric compounds dissociate in benzene or toluene at ambient temperature, and an equilibrium with the monomeric species is established. Variable-temperature 1H NMR spectroscopy showed that ΔH = -93 kJ/mol and ΔS = -285 J/(mol·K) for the dimerization of Me2BP(t-Bu)2 and ΔH = -55 ± 12 kJ/mol and ΔS = -166 ± 42 J/(mol·K) for the dimerization of Me2BP(SiMe3)2. Inverse 2D 1H/13C correlation studies were applied to monomer-dimer solutions and were vital to assignment of 13C resonances. Solid-state 31P NMR confirmed that [Me2BP(t-Bu)2]2 and [Me2BP(SiMe3)2]2 are dimeric solids. The structure of [Me2BP(t-Bu)2]2 was determined by single-crystal X-ray diffraction. Crystal data: triclinic, space group P1, a = 8.366(3) A?, b = 8.0808(2) A?, c = 9.311(2) A?, α = 74.98(2)°, β = 78.87(2)°, γ = 64.32(2)°, Z = 1, and R = 0.0628.