55271-06-2

Basic information

• Product Name: 3-(4-METHOXY-PHENYL)-1H-INDAZOLE
• Synonyms: 3-(4-METHOXY-PHENYL)-1H-INDAZOLE
• CAS NO: 55271-06-2
• Molecular Formula: C₁₄H₁₂N₂O
• Molecular Weight: 224.26
• Mol File: 55271-06-2.mol
• Article Data: 20

Chemical Properties

• Melting Point: 85-86 °C
• Boiling Point: 436.4±28.0 °C(Predicted)
• Appearance: /
• Density: 1.216±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 13.72±0.40(Predicted)
• CAS DataBase Reference: 3-(4-METHOXY-PHENYL)-1H-INDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-METHOXY-PHENYL)-1H-INDAZOLE(55271-06-2)
• EPA Substance Registry System: 3-(4-METHOXY-PHENYL)-1H-INDAZOLE(55271-06-2)

Safety Data

• Hazardous Substances Data: 55271-06-2(Hazardous Substances Data)

Usage

General Description

3-(4-Methoxy-phenyl)-1H-indazole is a chemical compound that belongs to the class of indazoles. It is characterized by the presence of a 4-methoxy-phenyl group attached to the indazole ring. 3-(4-METHOXY-PHENYL)-1H-INDAZOLE has been studied for its potential pharmacological properties and has been investigated as a potential drug candidate in pre-clinical research. Its molecular structure and properties make it a promising candidate for various medicinal applications, including as a potential therapeutic agent for a range of conditions. Research into its potential uses and effects is ongoing, and it shows promise as a versatile chemical compound with potential pharmaceutical applications.

Upstream product

• 5720-07-0 4-methoxyphenylboronic acid 
• 66607-27-0 3-iodoindazole 
• 40598-94-5 3-bromo-1H-indazole 
• 19350-72-2 N'-(4-methoxybenzylidene)-4-methylbenzenesulfonohydrazide 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 123-11-5 4-methoxy-benzaldehyde 
• 1373397-21-7 2-(trimethylsilyl)phenyl imidazol-1-sulfonate 
• 1441096-60-1 3-ethoxy-1-tosyl-1H-indazole 
• 825-60-5 benzimidic acid ethyl ester 
• 290368-00-2 tert-butyl 3-iodo-1H-indazole-1-carboxylate 
• 60869-95-6 3-bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole 
• 446-52-6 2-Fluorobenzaldehyde 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 944695-91-4 C₁₄H₁₃FO₂ 

Downstream Products

• 1569280-69-8 C₂₀H₁₇N₃O₃S 
• 1204771-24-3 C₁₈H₁₃N₃O₃S 
• 1451489-90-9 3-(4-methoxyphenyl)-1,2-dimethyl-2,3-dihydro-1H-indazole 
• 51093-44-8 3‐(4‐methoxyphenyl)‐1‐methyl‐1H‐indazole 

Relevant articles and documents

Arylation Using Sulfonamides: Phenylacetamide Synthesis through Tandem Acylation-Smiles Rearrangement

A range of electron-poor and heterocyclic sulfonamides react with phenylacetyl chlorides to produce benzhydryl derivatives in a single step. The reaction proceeds via tandem amide bond formation/Dohmori-Smiles rearrangement under the simple conditions of

A facile route to 1: H- A nd 2 H-indazoles from readily accessible acyl hydrazides by exploiting a novel aryne-based molecular rearrangement

Herein we report the transformation of readily synthesised acyl hydrazides into 2-hydrazobenzophenones via a novel molecular rearrangement pathway using aryne chemistry. The developed reaction protocol is performed under relatively mild conditions and is

Ni and Cu-catalyzed one pot synthesis of unsymmetrical 1,3-di(hetero)aryl-1: H -indazoles from hydrazine, o -chloro (hetero)benzophenones, and (hetero)aryl bromides

The nickel-catalyzed cyclization of in situ generated ortho-chlorobenzophenone hydrazone derivatives, to afford 3-(hetero)aryl-1H-indazoles, is documented for the first time. The product 1H-indazoles can be transformed subsequently in a one-pot procedure into 1,3-di(hetero)aryl-1H-indazoles via copper-catalyzed N-arylation with (hetero)aryl bromides.