55272-36-1

Basic information

• Product Name: [RuCl(η(5)-C5H4Me)(PPh3)2]
• Synonyms: [RuCl(η(5)-C5H4Me)(PPh3)2]
• CAS NO: 55272-36-1
• Molecular Weight: 740.226
• Mol File: 55272-36-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: [RuCl(η(5)-C5H4Me)(PPh3)2](CAS DataBase Reference)
• NIST Chemistry Reference: [RuCl(η(5)-C5H4Me)(PPh3)2](55272-36-1)
• EPA Substance Registry System: [RuCl(η(5)-C5H4Me)(PPh3)2](55272-36-1)

Safety Data

• Hazardous Substances Data: 55272-36-1(Hazardous Substances Data)

Upstream product

• 63767-78-2 ruthenium trichloride 
• 96-39-9 methylcyclopentadiene 
• 603-35-0 triphenylphosphine 
• 14898-67-0 ruthenium trichloride hydrate 
• 96-38-8 methylcyclopentadiene 

Downstream Products

• 217327-05-4 trans-[(η(5)-C5H4Me)(PPh3)2Ru-C.tplbond.C-p-C6H4-C.tplbond.C-Pt(Et3P)2(Ph)] 
• 107587-14-4 Ru(CH₃C₅H₄)(S₂CN(C₂H₅)2)(P(C₆H₅)3) 
• 107604-48-8 Ru(CH₃C₅H₄)(S₂CN(CH₂)4)(P(C₆H₅)3) 
• 107604-46-6 Ru(CH₃C₅H₄)(S₂COC₂H₅)(P(C₆H₅)3) 
• 107604-45-5 Ru(CH₃C₅H₄)(S₂COCH₃)(P(C₆H₅)3) 
• 107587-19-9 Ru(C₅H₄CH₃)(S₂COCH₃)(P(C₆H₅)3)2 
• 107604-47-7 Ru(CH₃C₅H₄)(S₂COC₆H₁₁)(P(C₆H₅)3) 
• 107587-15-5 Ru(CH₃C₅H₄)(S₂CCN)(P(C₆H₅)3)2 
• 139584-18-2 {(MeCp)Ru(PPh3)}2(μ-η1,η2-Se2)2(OTf)2 
• 110077-75-3 {MeCpRu(PPh3)2}2(μ-S2){BF4}2 

Relevant articles and documents

Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorinated ligand shows strong activity towards colorectal cancer cells

Three new compounds have been synthesized and completely characterized by analytical and spectroscopic techniques. The new bipyridine-perfluorinated ligand L1 and the new organometallic complex [Ru(η5-MeCp)(PPh3)2Cl] (Ru1) crystalize in the centrosymmetric triclinic space group P1ˉ. Analysis of the phenotypic effects induced by both organometallic complexes Ru1 and [Ru(η5-MeCp)(PPh3)(L1)][CF3SO3] (Ru2), on human colorectal cancer cells (SW480 and RKO) survival, showed that Ru2 has a potent anti-proliferative activity, 4–6 times higher than cisplatin, and induce apoptosis in these cells. Data obtained in a noncancerous cell line derived from normal colon epithelial cells (NCM460) revealed an intrinsic selectivity of Ru2 for malignant cells at low concentrations, showing the high potential of this compound as a selective anticancer agent.

Tandem transfer hydrogenation-epoxidation of ketone substrates catalysed by alkene-tethered Ru(ii)-NHC complexes

A series of nine cyclopentadienyl Ru(ii)-NHC complexes (1-9) have been synthesised by systematically varying the ligand and/or ligand substituents: η5-C5H4R′ (R′ = H, Me), EPh3 (E = P, As), NHC (Im, BIm), where NHC = Im(R)(R′) (R, R′ = Me, Bn, 4-NO2Bn, C2H4Ph, C4H7). Each of the Ru(ii)-NHC complexes features an N-alkenyl tether to attain bidentate NHC ligands. All complexes found application as catalysts in the tandem transfer hydrogenation and epoxidation reactions of carbonyl substrates. The catalytic activity of the complexes was shown to be similar, with efficiencies of up to 69% conversion after 18 hours and varying alcohol:epoxide selectivity for a variety of electronically diverse carbonyl substrates. Complex 3, with a nitro-containing substituent on the NHC ligand, was the only complex that showed preference for the alcohol product over the epoxide after 18 hours of reaction time.