55299-57-5

Basic information

• Product Name: N,O-Diacetyl-DL-Serine methyl ester
• Synonyms: N,O-Diacetyl-DL-Serine methyl ester
• CAS NO: 55299-57-5
• Molecular Formula: C₈H₁₃NO₅
• Molecular Weight: 203.19
• Mol File: 55299-57-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 160 °C(Press: 8 Torr)
• Appearance: /
• Density: 1.168±0.06 g/cm3(Predicted)
• PKA: 14.10±0.46(Predicted)
• CAS DataBase Reference: N,O-Diacetyl-DL-Serine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N,O-Diacetyl-DL-Serine methyl ester(55299-57-5)
• EPA Substance Registry System: N,O-Diacetyl-DL-Serine methyl ester(55299-57-5)

Safety Data

• Hazardous Substances Data: 55299-57-5(Hazardous Substances Data)

Upstream product

• 5619-04-5 methyl 2-amino-3-hydroxypropanoate hydrochloride 
• 75-36-5 acetyl chloride 
• 186581-53-3 diazomethane 
• 1068-84-4 2-aminomalonic acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 145235-85-4 methyl (Z)-2-acetamido-3-(4-acetoxy-2,6-dimethylphenyl)-2-propenoate 
• 145235-86-5 (S)-4-acetoxy-N-acetyl-2,6-dimethylphenylalanine methyl ester 
• 5429-56-1 N-Acetamidoacrylic acid 

Relevant articles and documents

Unexpectedly rigid short peptide foldamers in which NH-π and CH-π interactions are preserved in solution

NH-π and CH-π interactions, due to their weak character, are not easily identified in solution. We report a group of isolable short peptides with stable folds, in which NH-π and CH-π main chain-side chain interactions can be detected in solution by means

Synthesizing method using serine to prepare Ramipril key intermediate

The invention relates to a synthesizing method using serine to prepare a Ramipril key intermediate. The Ramipril key intermediate is 2-azabicyclo[3.3.0] octane-3-carboxylic acid hydrochloride or benzyl ester hydrochloride. The synthesizing method includes: using the serine as the initial raw material, and sequentially performing esterification, acyl chloride acylation, deacidification, Michael addition, hydrolysis and hydrogenation reduction to obtain the Ramipril key intermediate. The synthesizing method has the advantages that the key intermediate is synthesized by a five-step method, and the synthesizing method is cheap in raw material, environmentally friendly, simple in preparation process, simple to operate, mild in reaction condition, short in reaction cycle, convenient in post-treatment, low in equipment requirement, capable of avoiding heavy metal pollution and the use of expensive catalysts, few in three wastes, high in product yield and purity and suitable for industrial production.

Acetylation under ultrasonic conditions: Convenient preparation of N-acetylamino acids

An efficient and simple method of preparation of acetylamino acids from amino acids under ultrasonic conditions is described. The reactions proceed without racemization and the yields are almost quantitative.