553-63-9

Basic information

• Product Name: Dimethocaine Hydrochloride
• Synonyms: Larocaine hydrochloride;Dimethocaine hydrochloride;1-Propanol, 3-(diethylamino)-2,2-dimethyl-, 1-(4-aminobenzoate), hydrochloride (1:1);Larocaine HCl;3-(Diethylamino)-2,2-dimethyl-1-propanol 4-aminobenzoate hydrochloride;3-(diethylaMino)-2,2-diMethyl-1-Propanol 1-(4-aMinobenzoate) hydrochloride;3-(DiethylaMino)-2,2-diMethyl-1-propanol 1-(4-aMinobenzoate) HCl;1-AMinobenzoyl-2,2-diMethyl-3-diethylaMinopropanol Hydrochloride
• CAS NO: 553-63-9
• Molecular Formula: C16H26N2O2.ClH
• Molecular Weight: 314.854
• EINECS: 202-303-5
• Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals
• Mol File: 553-63-9.mol
• Article Data: 0

Chemical Properties

• Melting Point: 195-196℃
• Boiling Point: 403.5 °C at 760 mmHg
• Flash Point: 197.8 °C
• Appearance: /
• Density: 1.035 g/cm³
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Water (Slightly)
• CAS DataBase Reference: Dimethocaine Hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Dimethocaine Hydrochloride(553-63-9)
• EPA Substance Registry System: Dimethocaine Hydrochloride(553-63-9)

Safety Data

• Hazardous Substances Data: 553-63-9(Hazardous Substances Data)

Usage

Description

Dimethocaine Hydrochloride is a local anesthetic with stimulant properties, chemically resembling cocaine, and is used for forensic and research purposes. It is an off-white solid and has the potential for abuse due to its similarity in action to cocaine.

Uses

Used in Pharmaceutical Research:
Dimethocaine Hydrochloride is used as a research compound for studying its local anesthetic and stimulant properties. It is particularly useful in understanding the mechanisms of action and potential for abuse, as it shares similarities with cocaine.
Used in Forensic Analysis:
Dimethocaine Hydrochloride is employed as a forensic tool to analyze and identify its presence in cases related to substance abuse or criminal investigations.
Used in Drug Discrimination Tests:
Dimethocaine Hydrochloride is used as a test substance in drug discrimination tests for rats and rhesus monkeys, due to its dose-dependent substitution for cocaine in these tests.
Used in Inhibition Studies:
Dimethocaine Hydrochloride is utilized in studies to inhibit dopamine uptake in rat striatal synaptosomes, with an IC50 value comparable to that of cocaine, providing insights into the interactions between the compound and neurotransmitter systems.