55304-85-3

Basic information

• Product Name: 2,6-Dibromo-3-pyridinecarboxylic acid
• Synonyms: 2,6-Dibromo-3-pyridinecarboxylic acid;2,6-Dibromonicotinic acid;2,6-Dibromopyridine-3-carboxylic acid;2,6-DibroMopyridine-3-carboxylic
• CAS NO: 55304-85-3
• Molecular Formula: C6H3Br2NO2
• Molecular Weight: 280.9
• Product Categories: Heterocycle-Pyridine series
• Mol File: 55304-85-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 150 °C
• Boiling Point: 380.059°C at 760 mmHg
• Flash Point: 183.654°C
• Appearance: /
• Density: 2.202
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.652
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 1.89±0.10(Predicted)
• CAS DataBase Reference: 2,6-Dibromo-3-pyridinecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dibromo-3-pyridinecarboxylic acid(55304-85-3)
• EPA Substance Registry System: 2,6-Dibromo-3-pyridinecarboxylic acid(55304-85-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 55304-85-3(Hazardous Substances Data)

Usage

General Description

2,6-Dibromo-3-pyridinecarboxylic acid is a chemical compound with the molecular formula C7H4Br2NO2. It is derived from the pyridinecarboxylic acid family and contains two bromine atoms attached to the 2 and 6 positions of the pyridine ring. 2,6-Dibromo-3-pyridinecarboxylic acid is commonly used in organic synthesis and serves as a key intermediate in the production of various pharmaceuticals and agrochemicals. It is known for its high level of reactivity and is often employed in cross-coupling reactions and other organic transformations. Additionally, it has potential applications in the field of medicinal chemistry for drug discovery and development.

InChI:InChI=1/C6H3Br2NO2/c7-4-2-1-3(6(10)11)5(8)9-4/h1-2H,(H,10,11)

Upstream product

• 55304-83-1 2,6-dibromo-pyridine-3-carbaldehyde 
• 626-05-1 2,6-Dibromopyridine 
• 124-38-9 carbon dioxide 

Downstream Products

• 1009735-22-1 methyl 2,6-dibromopyridine-3-carboxylate 

Relevant articles and documents

BICYCLIC INHIBITORS OF ALK

The present invention relates to compounds of formula (1) or pharmaceutical acceptable salts, wherein R1, X, Y, Z, A, B, G1, and n are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as ALK and methods of treating diseases such as cancer.

NITROGENATED FUSED RING DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE OF THE SAME FOR MEDICAL PURPOSES

[Purpose] The present invention provides compounds useful as agents for the prevention or treatment of a sex hormone-dependent disease or the like. [Solution] The present invention provides nitrogen-containing fused ring derivatives represented by the following general formula (I) which has a GnRH antagonistic activity, prodrugs, salts, pharmaceutical compositions containing the same, medicinal uses thereof and the like. In the formula (I), rings A and B are independently aryl or heteroaryl; RA and RB are independently halogen, cyano, alkyl, alkylsulfonyl, -OW1, -SW1, -COW2, -NW3W4, -SO2NW3W4, aryl, etc.; RC is H or alkyl; E is oxygen atom, etc.; U is single bond or alkylene; and X is Y, -CO-Y, -SO2-Y -S-(alkylene)-Y, -O-(alkylene)-Y, -SO2-(alkylene)-Y, etc.; Y is Z or amino, etc.; and Z is cycloalkyl, heterocycloalkyl, aryl, heteroaryl, etc.