5531-98-6Relevant articles and documents
3,4-Dihydroxy- and 3,4-methylenedioxy- phenanthrene-type alkaloids with high selectivity for D2 dopamine receptor
Moreno, Laura,Cabedo, Nuria,Ivorra, Maria Dolores,Sanz, Maria-Jesus,Castel, Arturo Lopez,Carmen Alvarez,Cortes, Diego
, p. 4824 - 4827 (2013/09/02)
Dopamine-mediated neurotransmission plays an important role in relevant psychiatric and neurological disorders. Nowadays, there is an enormous interest in the development of new drugs acting at the dopamine receptors (DR) as potential new targets for the
Radical cyclization to dibenzo[de,g] chromanones. A new synthesis of phenanthrene compounds
Estevez, Juan C.,Villaverde, M. Carmen,Estevez, Ramon J.,Castedo, Luis
, p. 2783 - 2790 (2007/10/02)
We describe the radical cyclization of bromobenzylisochromanones to afford the novel dibenzo[de, g]chromanones. Opening the lactone ring of the latter allows the preparation of phenanthrene alkaloids and 1-phenanthrenylacetic acids.
TRANSFORMATION FROM APORPHINE N-OXIDES TO 1-(N-METHYL-N-HYDROXYLAMINOETHYL)PHENANTHRENE DERIVATIVES
Lu, Sheng-Teh,Wu, Yang-Chang
, p. 3085 - 3094 (2007/10/02)
Heat treatment of aporphine N-oxides prepared by the m-chloroperbenzoic acid (m-CPBA) oxidation of aporphines afforded 1-(N-methyl-N-hydroxylaminoethyl)phenanthrene derivatives which were characterized by the physical and chemical evidences.The biogenetic pathway from aporphines to phenanthrenes is also discussed.