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55314-49-3

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55314-49-3 Usage

Description

9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE, also known as PGF2α 1,15-lactone, is a lipid-soluble internal ester of PGF2α. It is a naturally occurring compound derived from the prostaglandin family, which are a group of bioactive lipid compounds involved in various physiological processes. The hydrolysis of the lactone group in PGF2α 1,15-lactone readily produces free PGF2α in plasma, making it an important precursor in the synthesis of this bioactive molecule.

Uses

Used in Pharmaceutical Industry:
PGF2α 1,15-lactone is used as a pharmaceutical agent for the termination of early pregnancy. In rhesus monkeys, a total dose of 15 mg of PGF2α 1,15-lactone has been shown to effectively terminate early pregnancy, whereas PGF2α alone is ineffective. This makes it a valuable compound in the development of medications for reproductive health and family planning.
Additionally, PGF2α and its derivatives, including PGF2α 1,15-lactone, have been studied for their potential applications in various other medical conditions, such as glaucoma, asthma, and other inflammatory disorders. However, further research is needed to fully understand the therapeutic potential and safety of PGF2α 1,15-lactone in these applications.

Check Digit Verification of cas no

The CAS Registry Mumber 55314-49-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,3,1 and 4 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 55314-49:
(7*5)+(6*5)+(5*3)+(4*1)+(3*4)+(2*4)+(1*9)=113
113 % 10 = 3
So 55314-49-3 is a valid CAS Registry Number.
InChI:InChI=1/C20H32O4/c1-2-3-6-9-15-12-13-17-16(18(21)14-19(17)22)10-7-4-5-8-11-20(23)24-15/h4,7,12-13,15-19,21-22H,2-3,5-6,8-11,14H2,1H3/b7-4+,13-12+/t15-,16+,17+,18-,19+/m0/s1

55314-49-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE

1.2 Other means of identification

Product number -
Other names pgf2-alpha1,15-lactone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:55314-49-3 SDS

55314-49-3Relevant articles and documents

Synthesis and biological activity of prostaglandin lactones

Bundy,Peterson,Cornette,Miller,Spilman,Wilks

, p. 1089 - 1099 (2007/10/02)

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