55331-64-1Relevant articles and documents
Glycosidation-anomerisation reactions of 6,1-anhydroglucopyranuronic acid and anomerisation of β-D-glucopyranosiduronic acids promoted by SnCl 4
O'Brien, Colin,Polakova, Monika,Pitt, Nigel,Tosin, Manuela,Murphy, Paul V.
, p. 902 - 909 (2007/10/03)
The reaction of silylated nucleophiles with 6,1-anhydroglucopyranuronic acid (glucuronic acid 6,1-lactones) catalysed by tin(IV) chloride provides 1,2-trans or 1,2-cis (deoxy)glycosides in a manner dependent on the donor structure. The α-glycoside was obt
Glucuronide and sulfate conjugates of ICI 182,780, a pure anti- estrogenic steroid. Order of addition, catalysis and substitution effects in glucuronidation
Ferguson, John R.,Harding, John R.,Lumbard, Keith W.,Scheinmann, Feodor,Stachulski, Andrew V.
, p. 389 - 392 (2007/10/03)
The 3-sulfate 4 and 3- and 17-glucuronide conjugates 5 and 6 of the pure anti-estrogenic steroid ICI 182,780 1, which is expected to be an effective agent for the treatment of breast cancer, have been prepared. The synthesis of 6 could only be satisfactorily achieved using an inverse addition technique, not previously employed in the glucuronic acid series: the value of this technique for some other aglycones is discussed.