5534-02-1

Basic information

• Product Name: BETAMETHASONE BUTYRATE PROPIONATE
• Synonyms: BETAMETHASONE BUTYRATE PROPIONATE;9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-butyrate 21-propionate;Anflavate;Antebate;Betamethasone 17-butyrate 21-propionate;Salex;[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] butanoate;[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] butanoate
• CAS NO: 5534-02-1
• Molecular Formula: C29H39FO7
• Molecular Weight: 518.61
• Mol File: 5534-02-1.mol
• Article Data: 0

Chemical Properties

• Melting Point: approximate 152℃
• Boiling Point: 613°Cat760mmHg
• Flash Point: 324.5°C
• Appearance: /
• Density: 1.23g/cm³
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Dioxane (Slightly, Sonicated), Methanol (Slightly)
• PKA: 12.88±0.70(Predicted)
• CAS DataBase Reference: BETAMETHASONE BUTYRATE PROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: BETAMETHASONE BUTYRATE PROPIONATE(5534-02-1)
• EPA Substance Registry System: BETAMETHASONE BUTYRATE PROPIONATE(5534-02-1)

Safety Data

• Hazardous Substances Data: 5534-02-1(Hazardous Substances Data)

Usage

Description

Betamethasone butyrate propionate (BBP) was introduced in Japan as a topical antiinflammatory agent. It is a synthetic corticosteroid with strong antiinflammatory activity at the site of inflammation but without topical or systemic side effects. On paper disk granuloma in rats, BBP was shown to have higher degree of dissociation between antiinflammation efficacy and systemic side effects than other agents in this class. Antipyretic/analgesic properties have also been reported.

Originator

Mitsubishi Kasai (Japan)

Uses

Betamethasone-17-butyrate-21-propionate are used in the treatment of vitiligo vulgaris with the combination therapy of topical steroid and vitamin D3 compound.

Brand name

Antebate; Antevate