5535-87-5

Basic information

• Product Name: 3,5-Diaminobenzoic acid
• Synonyms: 1,6-Dioxaspiro[4.5]dec-3-ene, 2-(2,4-hexadiyn-1-ylidene)-, (2Z)-
• CAS NO: 5535-87-5
• Molecular Formula: C14H14O2
• Molecular Weight: 214.26
• Mol File: 5535-87-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,5-Diaminobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Diaminobenzoic acid(5535-87-5)
• EPA Substance Registry System: 3,5-Diaminobenzoic acid(5535-87-5)

Safety Data

• Hazardous Substances Data: 5535-87-5(Hazardous Substances Data)

Upstream product

• 215169-26-9 1-[5-(4-Hydroxy-butyl)-furan-2-yl]-hexa-2,4-diyn-1-ol 
• 19958-66-8 4-(furan-2-yl)butan-1-ol 
• 79011-51-1 α-Furyl-1 acetoxy-4 butane 
• 112897-42-4 5-(4-acetoxybutyl)-2-furaldehyde 
• 215169-25-8 Acetic acid 4-[5-(1-hydroxy-hexa-2,4-diynyl)-furan-2-yl]-butyl ester 
• 1086594-84-4 5-(hexa-2,4-diynyl)-2-(4-hydroxybutyl)furan 

Relevant articles and documents

A straightforward synthetic approach to the spiroketal-enol ethers synthesis of natural antifeeding compound tonghaosu and its analogs

Tonghaosu 1, a natural product discovered from several plants of tribe Athemdeae, is a [4.4]spiroketal with an enediyne side-chain and shows interesting insect antifeeding activity. In this paper a general and convenient synthetic methodology for the synthesis of 1, 2 and its spiroketal-enol ether derivatives is described. Thus, 3-(2'-furyl)-propan-1- ol 7a or 4-(2'-furyl)-butan-1-ol 7b prepared from furaldehyde was treated with n-butyl lithium and unsaturated aldehyde to provide the diol 5. Diol 5 could also be obtained from 5-(3-acetoxypropyl)-2-furaldehyde or 5-(4- acetoxybutyl)-2-furaldehyde and alkynyllithium. By careful treatment of 5 or 7 with acid, dehydration-cyclization occurred to give the desired spiroketal- enol ether in moderate to excellent yields.