55359-96-1

Basic information

• Product Name: 5-Thiazolecarboxaldehyde, 4-chloro-2,3-dihydro-2-oxo-
• Synonyms: 5-Thiazolecarboxaldehyde, 4-chloro-2,3-dihydro-2-oxo-;4-chloro-2-oxo-2,3-dihydrothiazole-5-carbaldehyde;4-Chloro-2,3-dihydro-2-oxo-5-thiazolecarboxaldehyde;4-chloro-2-oxo-3H-1,3-thiazole-5-carbaldehyde
• CAS NO: 55359-96-1
• Molecular Formula: C₄H₂ClNO₂S
• Molecular Weight: 163.58
• Product Categories: API intermediates
• Mol File: 55359-96-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.68g/cm³
• Refractive Index: 1.637
• PKA: 5.46±0.60(Predicted)
• CAS DataBase Reference: 5-Thiazolecarboxaldehyde, 4-chloro-2,3-dihydro-2-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Thiazolecarboxaldehyde, 4-chloro-2,3-dihydro-2-oxo-(55359-96-1)
• EPA Substance Registry System: 5-Thiazolecarboxaldehyde, 4-chloro-2,3-dihydro-2-oxo-(55359-96-1)

Safety Data

• Hazardous Substances Data: 55359-96-1(Hazardous Substances Data)

Usage

General Description

5-Thiazolecarboxaldehyde, 4-chloro-2,3-dihydro-2-oxo- is a chemical compound with a thiazole structure and a chloro substitution at the 4-position. It is also known as 4-chloro-2,3-dihydrothiazole-4-carbaldehyde. 5-Thiazolecarboxaldehyde, 4-chloro-2,3-dihydro-2-oxo- is commonly used as a building block in organic synthesis and is a key intermediate in the production of pharmaceuticals, agrochemicals, and other fine chemicals. It is known to exhibit a range of biological activities and has been the subject of research for its potential medicinal and industrial applications. Its unique structure and reactivity make it a valuable component in the development of novel chemical compounds.

InChI:InChI=1/C4H2ClNO2S/c5-3-2(1-7)9-4(8)6-3/h1H,(H,6,8)

Upstream product

• 2295-31-0 thiazoline-2,4-dione 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 127868-42-2 C₁₀H₈N₂O₂S 
• 87423-04-9 2-Oxo-8-methylthio-6-phenyl-1,2-dihydrothiazolo<3,4-a>pyrimidinium benzenesulfonate 
• 127868-41-1 C₁₆H₁₂N₂O₂S 
• 87243-13-8 C₂₁H₂₀N₄O₂S*ClH 
• 848691-22-5 5-aminothiazolo[4.5-d]pyrimidine-2,7-(3H,6H)-dione 

Relevant articles and documents

First synthesis of novel aminophenyl pyridinium-5-(hydroxybenzoyl)-hydrazonomethyl-2-oxothiazol-3-ide derivatives and evaluation of their anticancer activities

The first total synthesis for large-scale production and anticancer activity of novel aminophenylpyridinium-5-(hydroxybenzoyl)hydrazonomethyl-2-oxothiazol-3-ide (PBHT) (1) and its derivatives are reported. The chemical structure of PBHT was unambiguously

3-β-D-RIBOFURANOSYLTHIAZOLO[4,5-d]PYRIDIMINE NUCLEOSIDES AND USES THEREOF

The invention is directed to 3-?-D-ribofuranosylthiazolo[4,5-d]pyridimine nucleosides and pharmaceutical compositions containing such compounds that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic use of such compounds and compositions, and to methods of treating diseases and disorders described herein, by administering effective amounts of such compounds.