55440-17-0

Basic information

• Product Name: 3-(trifluoromethyl)-1H-indazole
• Synonyms: 3-(trifluoromethyl)-1H-indazole;3-AMino-4,5,6,7-tetrahydro-1H-indazole;3-chloro-4,5,6,7-tetrahydro-1H-indazole;3-Amino-4,5,6,7-tetrahydroindazole
• CAS NO: 55440-17-0
• Molecular Formula: C8H5F3N2
• Molecular Weight: 186.1339096
• Mol File: 55440-17-0.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.246±0.06 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility: DMSO (Slightly, Heated), Methanol (Slightly)
• CAS DataBase Reference: 3-(trifluoromethyl)-1H-indazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(trifluoromethyl)-1H-indazole(55440-17-0)
• EPA Substance Registry System: 3-(trifluoromethyl)-1H-indazole(55440-17-0)

Safety Data

• Hazardous Substances Data: 55440-17-0(Hazardous Substances Data)

Usage

Description

3-(trifluoromethyl)-1H-indazole, also known as TFI, is a heterocyclic organic compound with the molecular formula C8H5F3N2. It consists of a five-membered ring with three carbon atoms, one nitrogen atom, and one fluorine atom, along with a trifluoromethyl group. TFI is a white crystalline powder that is sparingly soluble in water but soluble in organic solvents. It has potential applications in pharmaceutical and agrochemical industries, where it can be used as a building block in the synthesis of various biologically active compounds. TFI has also been studied for its potential anti-inflammatory and anti-cancer properties, making it a subject of interest in medicinal chemistry research. Additionally, its trifluoromethyl group makes it an attractive target for fluorine-18 labeling in positron emission tomography (PET) imaging studies.

Uses

Used in Pharmaceutical Industry:
3-(trifluoromethyl)-1H-indazole is used as a building block for the synthesis of biologically active compounds due to its unique chemical structure and potential anti-inflammatory and anti-cancer properties.
Used in Agrochemical Industry:
3-(trifluoromethyl)-1H-indazole is used as a building block in the development of agrochemicals, leveraging its potential to create new compounds with desired biological activities.
Used in Medicinal Chemistry Research:
3-(trifluoromethyl)-1H-indazole is used as a subject of interest for its potential anti-inflammatory and anti-cancer properties, contributing to the discovery of new therapeutic agents.
Used in Positron Emission Tomography (PET) Imaging Studies:
3-(trifluoromethyl)-1H-indazole is used as a target for fluorine-18 labeling, enabling its application in PET imaging studies to visualize biological processes in vivo.