55502-61-9

Basic information

• Product Name: 2-CYANO-3-(3,4-DIMETHOXYPHENYL)-PROPIONIC ACID
• Synonyms: 2-CYANO-3-(3,4-DIMETHOXYPHENYL)-PROPIONIC ACID
• CAS NO: 55502-61-9
• Molecular Formula: C₁₂H₁₃NO₄
• Molecular Weight: 235.24
• Mol File: 55502-61-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 417.1°C at 760 mmHg
• Flash Point: 206.1°C
• Appearance: /
• Density: 1.227g/cm³
• Vapor Pressure: 1.05E-07mmHg at 25°C
• Refractive Index: 1.537
• CAS DataBase Reference: 2-CYANO-3-(3,4-DIMETHOXYPHENYL)-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYANO-3-(3,4-DIMETHOXYPHENYL)-PROPIONIC ACID(55502-61-9)
• EPA Substance Registry System: 2-CYANO-3-(3,4-DIMETHOXYPHENYL)-PROPIONIC ACID(55502-61-9)

Safety Data

• Hazardous Substances Data: 55502-61-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H13NO4/c1-16-10-4-3-8(6-11(10)17-2)5-9(7-13)12(14)15/h3-4,6,9H,5H2,1-2H3,(H,14,15)

Upstream product

• 86213-20-9 2-cyano-3-(3,4-dimethoxyphenyl)acrylic acid 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 37389-84-7 ethyl 2-cyano-3-(3,4-dimethoxyphenyl)propanoate 

Downstream Products

• 49621-56-9 3-(3,4-dimethoxyphenyl)propanenitrile 
• 892804-86-3 1-(2'-bromo-4',5'-dimethoxybenzyl)-7,8-dimethoxy-4,5-dihydro-3H-benzo[c]azepine 
• 14773-42-3 3-(3,4-dimethoxyphenyl)propylamine 
• 65548-33-6 1-[2-(2'-bromo-4',5'-dimethoxyphenyl)ethyl]-7,8-dimethoxy-4,5-dihydro-3H-benzo[c]azepine 
• 65004-82-2 2-(2'-bromo-4',5'-dimethoxyphenyl)-N-[3-(3',4'-dimethoxyphenyl)propyl]acetamide 
• 65548-31-4 2-(2'-bromo-4',5'-dimethoxyphenyl)-N-[3-(3',4'-dimethoxyphenyl)propyl]propionamide 
• 128995-99-3 1-(2,4-dihydroxyphenyl)-3-(3,4-dimethoxyphenyl)propane-1-one 
• 106648-24-2 5,6-dimethoxy-1-oxo-2,3-dihydro-1H-indene-2-carbonitrile 
• 120014-06-4 donepezil 

Relevant articles and documents

Double decarboxylative route to 3-substituted pyrrolidines: Reaction of monoalkyl malonates and related carboxylic acids with sarcosine and formaldehyde

Three-component reactions of monoalkyl malonates, cyanoacetic acids or 2-ketocarboxylic acids, N-methylglycine, and formaldehyde were developed to rapidly access 3-substituted pyrrolidines in 17–97% yield. These reactions represent a double decarboxylative domino-sequence promoted by pyrrolidine and involve N-methylazomethine ylide as the reactive intermediate.

The palladium-catalyzed preparation of condensed tetracyclic heterocycles and their application to the synthesis of rac-mangochinine

Dihydroisoquinoline derivatives and their analogues, prepared by the Bischler-Napieralsky reaction, were converted to their indole-fused derivatives. Scope and limitations of the palladium-catalyzed reaction, proceeding through the tautomeric enamine forms of these compounds, were studied and the process was extended to the preparation of racemic mangochinine. Georg Thieme Verlag Stuttgart.