55555-97-0 Usage
Description
6β-Hydroxy Norgestrel, also known as 6β-Hydroxylevonorgestrel, is a hydroxylated impurity derived from the synthesis of Levonorgestrel (N689510), which is an oral contraceptive. It is characterized by the presence of an additional hydroxyl group at the 6β position, distinguishing it from the parent compound.
Uses
Used in Pharmaceutical Industry:
6β-Hydroxy Norgestrel is used as an impurity in the synthesis of Levonorgestrel, an oral contraceptive. Its presence is significant as it can impact the efficacy and safety of the final product. The pharmaceutical industry is responsible for monitoring and controlling the levels of this impurity to ensure the quality and effectiveness of contraceptive medications.
Used in Quality Control and Regulatory Compliance:
6β-Hydroxy Norgestrel is used as a reference compound for quality control and regulatory compliance purposes in the pharmaceutical industry. It helps in the development and validation of analytical methods to detect and quantify impurities in active pharmaceutical ingredients, ensuring that the final products meet the required safety and efficacy standards.
Used in Research and Development:
6β-Hydroxy Norgestrel serves as a valuable compound for research and development in the pharmaceutical sector. It can be used to study the effects of structural modifications on the pharmacological properties of norgestrel and its derivatives, potentially leading to the discovery of new drugs with improved characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 55555-97-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,5,5 and 5 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 55555-97:
(7*5)+(6*5)+(5*5)+(4*5)+(3*5)+(2*9)+(1*7)=150
150 % 10 = 0
So 55555-97-0 is a valid CAS Registry Number.
55555-97-0Relevant articles and documents
A new metabolite from Cunninghamella blakesleeana-mediated biotransformation of an oral contraceptive drug, levonorgestrel
Kudaibergenova, Bates Malikovna,Wahab, Atia-tul-,Siddiqui, Mahwish,Abilov, Zharylkasyn A.,Choudhary, M. Iqbal
, p. 2095 - 2098 (2021)
Cunninghamella blakesleeana-mediated biotransformation of an oral contraceptive drug, levonorgestrel (1), yielded a new metabolite, 13β-ethyl-17α-ethynyl-10,17β-dihydroxy-4,6-dien-3-one (2), and two known metabolites 3 (13β-ethyl-17α-ethynyl-10β,17β-dihydroxy-4-en-3-one), and 4 (13β-ethyl-17α-ethynyl-6β,17β-dihydroxy-4-en-3-one) at an ambient temperature using aqueous media. Hydroxylation and dehydrogenation of compound 1 was observed during the bio-catalytic transformation. The structure of a new metabolite 2 was determined by 1H, 13C, and 2DNMR and HR-EIMS spectroscopic techniques.
