55581-61-8

Basic information

• Product Name: 3-Benzofurancarboxaldehyde, 2-methyl-
• Synonyms: 3-Benzofurancarboxaldehyde, 2-methyl-
• CAS NO: 55581-61-8
• Molecular Formula: C₁₀H₈O₂
• Molecular Weight: 160.17
• Mol File: 55581-61-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Benzofurancarboxaldehyde, 2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Benzofurancarboxaldehyde, 2-methyl-(55581-61-8)
• EPA Substance Registry System: 3-Benzofurancarboxaldehyde, 2-methyl-(55581-61-8)

Safety Data

• Hazardous Substances Data: 55581-61-8(Hazardous Substances Data)

Upstream product

• 4265-25-2 2-methylbenzofuran 
• 68-12-2 N,N-dimethyl-formamide 
• 10025-87-3 trichlorophosphate 
• 271-89-6 1-benzofurane 
• 4265-16-1 2-formylbenzo[b]furan 
• 4885-02-3 Dichloromethyl methyl ether 

Downstream Products

• 3782-00-1 2,3-dimethylbenzofuran 
• 138552-58-6 2-methyl-3-vinylbenzofuran 
• 138552-76-8 9a-methyl-N-phenyl-1,2,3,9a-tetrahydrobenzofuro<2,3-c>pyridazine-1,2-dicarboximide 

Relevant articles and documents

Synthesis of Chiral Polycyclic Tetrahydrocarbazoles by Enantioselective Aminocatalytic Double Activation of 2-Hydroxycinnamaldehydes with Dienals

An efficient aminocatalytic enantioselective double-activation strategy has been developed that combines several different aminocatalytic modes in a cascade process, such as iminium ion, vinylogous iminium ion, trienamine, and dienamine activations. By using this strategy, 2-hydroxycinnamaldehydes worked well with various dienals via [4 + 2] cycloaddition and the oxa-Michael reaction-initiated cascade, respectively, leading to chiral polycyclic tetrahydrocarbazole and chromane derivatives with excellent diastereo- and enantioselectivities.

Palladium-catalysed annulative allylic alkylation for the synthesis of benzannulated heteroarenes

A conceptually novel intramolecular allylic alkylation strategy is developed for the synthesis of carbazoles and dibenzothiophenes. In an unusual event, palladium catalyses the formation of π-allylpalladium complexes of the respective (2-methylindol-3-yl)allyl acetates and subsequently facilitates the benzannulation process. This journal is

Cyclopenta[b]annulation of Heteroarenes by Organocatalytic γ′[C(sp3)?H] Functionalization of Ynones

A new approach for the cyclopenta[b]annulation of heteroarenes through metal-free and directing-group-free γ′[C(sp3)?H] functionalization and intramolecular hydroalkylation of ynones has been developed. In an unprecedented event, nucleophilic addition of an organophosphine to the designed ynones triggers γ′[C(sp3)?H] functionalization, leading to the formation of heteroaryl-based ortho-quinodimethane (oQDM) intermediates that undergo carbocyclization to provide cyclopentannulated heteroarenes in good yields and excellent stereoselectivities. Deuterium-labeling experiments substantiated the proposed reaction mechanism as well as the speculated epimerization.