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556112-21-1

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556112-21-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 556112-21-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,6,1,1 and 2 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 556112-21:
(8*5)+(7*5)+(6*6)+(5*1)+(4*1)+(3*2)+(2*2)+(1*1)=131
131 % 10 = 1
So 556112-21-1 is a valid CAS Registry Number.

556112-21-1Relevant articles and documents

Novel 3-phenylprop-2-ynylamines as inhibitors of mammalian squalene epoxidase.

Musso, David L,Clarke, Morris J,Kelley, James L,Boswell, G Evan,Chen, Grace

, p. 498 - 506 (2003)

The synthesis of a novel series of 3-phenylprop-2-ynylamines as selective mammalian squalene epoxidase inhibitors is described. Structure activity relationship studies led to the discovery of compound 19, 1-[3-(3,5-dichlorophenyl)-prop-2-ynyl]-3- methylpiperidine hydrochloride with an IC50 of 2.8 +/- 0.6 microM against rat liver squalene epoxidase. Against 23 strains of fungal squalene epoxidase compound 19 was found to be inactive.

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