55631-11-3

Basic information

• Product Name: 1-chloro-4-(1-phenoxypropyl)benzene
• Synonyms: 1-chloro-4-(1-phenoxypropyl)benzene
• CAS NO: 55631-11-3
• Molecular Weight: 246.737
• Mol File: 55631-11-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-chloro-4-(1-phenoxypropyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-4-(1-phenoxypropyl)benzene(55631-11-3)
• EPA Substance Registry System: 1-chloro-4-(1-phenoxypropyl)benzene(55631-11-3)

Safety Data

• Hazardous Substances Data: 55631-11-3(Hazardous Substances Data)

Upstream product

• 108-95-2 phenol 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 19962-25-5 1-chloro-4-(phenoxymethyl)benzene 
• 75-03-6 ethyl iodide 

Relevant articles and documents

α-Lithiated Aryl Benzyl Ethers: Inhibition of [1,2]-Wittig Rearrangement and Application to the Synthesis of Benzo[b]furan Derivatives

The use of t-BuLi at low temperature selectively leads to α-lithiation of benzyl phenyl ether generating a stable organolithium, which can be efficiently trapped with a variety of selected electrophiles prior to suffering the expected [1,2]-Wittig rearrangement. In the case of (o-alkynyl)phenyl benzyl ethers, the intermediate α-aryloxyorganolithium undergoes an unexpected anti intramolecular carbolithiation reaction leading to functionalized benzo[b]furan derivatives.