55726-47-1 Usage
Description
Enocitabine, also known as SUNRABIN, is an antileukemic agent closely related to cytarabine. It is a crystalline solid that exhibits more resistance to deamination than cytarabine, allowing for greater in vivo phosphorylation into an active cytotoxic metabolite.
Uses
Used in Oncology:
Enocitabine is used as an antineoplastic agent, specifically as a derivative of cytarabine, for the treatment of various types of cancer. Its increased resistance to deamination compared to cytarabine enables more efficient conversion into an active cytotoxic metabolite, making it a valuable option in cancer treatment.
Used in Pharmaceutical Industry:
Enocitabine is used as an active pharmaceutical ingredient in the development of cancer treatment drugs. Its unique properties, such as greater resistance to deamination, make it a promising candidate for the creation of more effective and targeted cancer therapies.
Used in Research and Development:
Enocitabine is utilized as a research compound in the field of oncology, where scientists study its properties, mechanisms of action, and potential applications in cancer treatment. This research can lead to the development of new drugs and therapies that build upon the unique characteristics of enocitabine.
Originator
Asahi (Japan)
Check Digit Verification of cas no
The CAS Registry Mumber 55726-47-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,7,2 and 6 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 55726-47:
(7*5)+(6*5)+(5*7)+(4*2)+(3*6)+(2*4)+(1*7)=141
141 % 10 = 1
So 55726-47-1 is a valid CAS Registry Number.
InChI:InChI=1/C31H55N3O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-27(36)32-26-22-23-34(31(39)33-26)30-29(38)28(37)25(24-35)40-30/h22-23,25,28-30,35,37-38H,2-21,24H2,1H3,(H,32,33,36,39)/t25-,28-,29+,30-/m1/s1
55726-47-1Relevant articles and documents
TRANSDERMAL DEVICE CONTAINING POLYVINYLPYRROLIDONE AS SOLUBILITY ENHANCER
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, (2008/06/13)
A blend of at least three polymers, including a soluble polyvinylpyrrolidone, in combination with a drug provides a pressure-sensitive adhesive composition for a transdermal drug delivery system in which the drug is delivered from the pressure-sensitive adhesive composition and through dermis when the pressure-sensitive adhesive composition is in contact with human skin. Soluble polyvinylpyrrolidone increases the solubility of drug without negatively affecting the adhesivity of the composition or the rate of drug delivery from the pressure-sensitive adhesive composition
