55837-25-7

Basic information

• Product Name: Buflomedil
• Synonyms: 1-Butanone, 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-;2',4',6'-Trimethoxy-4-(1-pyrrolidinyl)butyrophenone;4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanon;4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone;AURORA KA-850;BUFLOMEDIL;BufluomedilHcl;Buflomedil Hcl 35543-24-9 / Base
• CAS NO: 55837-25-7
• Molecular Formula: C₁₇H₂₅NO₄
• Molecular Weight: 307.38
• EINECS: 259-851-3
• Product Categories: Pharmaceutical;Active Pharmaceutical Ingredients;API;Adrenoceptor
• Mol File: 55837-25-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 454.5 °C at 760 mmHg
• Flash Point: 228.7 °C
• Appearance: /
• Density: 1.09 g/cm³
• Vapor Pressure: 1.9E-08mmHg at 25°C
• Refractive Index: 1.519
• PKA: 10.15±0.20(Predicted)
• CAS DataBase Reference: Buflomedil(CAS DataBase Reference)
• NIST Chemistry Reference: Buflomedil(55837-25-7)
• EPA Substance Registry System: Buflomedil(55837-25-7)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: EL9885000
• Hazardous Substances Data: 55837-25-7(Hazardous Substances Data)

Usage

Uses

BAN; DCF; MI.

Therapeutic Function

Vasodilator

InChI:InChI=1/C17H25NO4/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18/h11-12H,4-10H2,1-3H3

Relevant articles and documents

Topical medicament which increases the number of capillaries in damaged skin

A method for increasing the number of capillaries in damaged skin during healing of the skin is disclosed. The method includes the application of a skin composition to the damaged skin which comprises an active compound having peripheral vasokinetic activity and a pharmaceutically acceptable carrier. The active compound is selected from compounds such as Amni visnaga coumarins, Vinca alkaloids, Ergot alkaloids, polyunsaturated fatty acid derivatives, a buflomedil bioflavinoid, Ginkgo bioflavonoids, and Cratageus bioflavonoids. The composition is applied in amount to increase the number of capillaries in new tissue which forms during healing of the damaged skin. Furthermore, a method of treating bedsores is also disclosed.