5584-30-5Relevant articles and documents
Studies with enamines: Route to aminoazolopyrimidines and arylazoazolopyrimidines
Salaheldin, Abdellatif M.,Khairou, Khalid S.
, p. 175 - 181 (2013/04/23)
An easy preparation of enaminonitrile derivatives and their transformation into new substituted azolopyrimidines is described. The one-step transformation was carried out under microwave irradiation and by classical heating methods. The use of microwave i
New pyrazolo[1,5a]pyrimidines as orally active inhibitors of Lck
Gommermann, Nina,Buehlmayer, Peter,Von Matt, Anette,Breitenstein, Werner,Masuya, Keiichi,Pirard, Bernard,Furet, Pascal,Cowan-Jacob, Sandra W.,Weckbecker, Gisbert
scheme or table, p. 3628 - 3631 (2010/09/04)
A novel series of pyrazolo[1,5a]pyrimidines was optimized to target lymphocyte-specific kinase (Lck). An efficient synthetic route was developed and SAR studies toward activity and selectivity are described, leading to Lck inhibitors with enzymatic, cellu
PYRAZOLO [1, 5-A] PYRIMIDINE DERIVATIVES AND THEIR THERAPEUTIC USE
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Page/Page column 8, (2008/06/13)
Disclosed are pyrazolo-pyrimidine derivatives which have interesting pharmaceutical properties.