558437-61-9Relevant articles and documents
Intramolecular Oxidative Coupling between Unactivated Aliphatic C-H and Aryl C-H Bonds
Liao, Yang,Zhou, Yi,Zhang, Zhen,Fan, Junzhen,Liu, Feng,Shi, Zhangjie
supporting information, p. 1251 - 1257 (2021/03/03)
Direct oxidative coupling of different inert C-H bonds is the most straightforward and environmentally benign method to construct C-C bonds. In this paper, we developed a Pd-catalyzed intramolecular oxidative coupling between unactivated aliphatic and aryl C-H bonds. This chemistry showed great potential to build up fused cyclic scaffolds from linear substrates through oxidative couplings. Privileged chromane and tetralin scaffolds were constructed from readily available linear starting materials in the absence of any organohalides and organometallic partners.
Synthesis of 2,2-dimethyl-1,25-dihydroxyvitamin D3: A-ring structural motif that modulates interactions of vitamin D receptor with transcriptional coactivators
Fujishima, Toshie,Kittaka, Atsushi,Yamaoka, Kazuyoshi,Takeyama, Ken-Ichi,Kato, Shigeaki,Takayama, Hiroaki
, p. 1863 - 1869 (2007/10/03)
A concise synthesis of all four possible A-ring stereoisomers of 2,2-dimethyl-1,25-dihydroxyvitamin D3 and characterization of their distinct transcriptional features, which appear to have been inherited from the corresponding 2α-methyl derivatives, is reported.