55870-50-3 Usage
Description
Ammonium (-)-3-bromo-8-camphorsulfonate is a chemical compound derived from camphor, a naturally occurring substance found in the camphor tree. It is characterized by its unique structure, which includes a bromo group and a camphorsulfonate group. Ammonium (-)-3-bromo-8-camphorsulfonate is known for its ability to form optically active resolutions, making it a valuable component in various chemical and pharmaceutical applications.
Uses
Used in Optical Resolutions:
Ammonium (-)-3-bromo-8-camphorsulfonate is used as a resolving agent for bromocamphor solutions in the field of optical resolutions. Its ability to form optically active resolutions is crucial for the separation of enantiomers, which are molecules that are mirror images of each other but have different biological activities. This application is particularly important in the pharmaceutical industry, where the development of pure enantiomers is essential for creating effective and safe drugs.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Ammonium (-)-3-bromo-8-camphorsulfonate is used as a key intermediate in the synthesis of various chiral drugs. Its role in optical resolutions allows for the production of single-enantiomer drugs, which can have significant implications for the efficacy and safety of medications. By ensuring that only the desired enantiomer is present in a drug, the risk of adverse effects caused by the undesired enantiomer can be minimized.
Used in Chemical Synthesis:
Ammonium (-)-3-bromo-8-camphorsulfonate is also utilized in the chemical synthesis of various compounds, particularly those with chiral centers. Its unique structure and optically active resolutions make it a valuable building block for the creation of complex molecules with specific stereochemistry. This application is relevant in various chemical industries, including the production of specialty chemicals, fragrances, and agrochemicals.
Purification Methods
Pass a hot aqueous solution of it through an alumina column to remove water-soluble coloured impurities which remain on the column when the ammonium salt is eluted with hot water. The salt is crystallised from water and dried over CaCl2 in a desiccator [Craddock & Jones J Am Chem Soc 84 1098 1962, Kauffmann J Prakt Chem 33 295 1966]. [Beilstein 11 H 319, 11 I 77, 11, II 183, 11 III 595.]
Check Digit Verification of cas no
The CAS Registry Mumber 55870-50-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,8,7 and 0 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 55870-50:
(7*5)+(6*5)+(5*8)+(4*7)+(3*0)+(2*5)+(1*0)=143
143 % 10 = 3
So 55870-50-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H15BrO4S.H3N/c1-9-4-3-6(7(11)8(9)12)10(9,2)5-16(13,14)15;/h6-7H,3-5H2,1-2H3,(H,13,14,15);1H3/t6-,7+,9+,10?;/m0./s1
