5594-07-0Relevant articles and documents
β-Carbolines: synthesis of harmane, harmine alkaloids and their structural analogs by thermolysis of 4-aryl-3-azidopyridines and investigation of their optical properties
Shuvalov, Vladislav Yu.,Elisheva, Valeriya А.,Belousova, Anastasiya S.,Arshinov, Evgenii V.,Glyzdinskaya, Larisa V.,Vorontsova, Marina А.,Chernenko, Sergei А.,Fisyuk, Aleksander S.,Sagitullina, Galina P.
, p. 73 - 83 (2020/02/18)
[Figure not available: see fulltext.] Interest in β-carbolines is caused by the biological activity of these compounds and the use of their fluorescent properties in the study of their interaction with DNA and other biological targets, as well as with drug delivery vehicles. A new general method for the synthesis of harmane, harmine, and their structural analogs by thermolysis of substituted 4-aryl-3-azidopyridines was developed, and their optical properties were studied.
A Convenient Synthesis of 3-Cyano-2-methylpyridines under Ultrasonic Irradiation
Shibata, Katsuyoshi,Urano, Katsuyoshi,Matsui, Masaki
, p. 2199 - 2200 (2007/10/02)
Ultrasonic irradiation of α,β-unsaturated carbonyl compounds 1a-i with acetonitrile in the presence of pottasium t-butoxide gave 3-cyano-2-methylpyridines 2a-i in moderate to good yields.The pyridines are produced by a Michael reaction of 3-iminobutanonitrile, an acetonitrile dimer, to the substrates 1a-i.
