55943-46-9

Basic information

• Product Name: (S)-2-Amino-3-(3,4-dihydroxy-phenyl)-2-methyl-propionic acid 3-acetylamino-propyl ester
• CAS NO: 55943-46-9
• Molecular Weight: 310.35
• Mol File: 55943-46-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-Amino-3-(3,4-dihydroxy-phenyl)-2-methyl-propionic acid 3-acetylamino-propyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-Amino-3-(3,4-dihydroxy-phenyl)-2-methyl-propionic acid 3-acetylamino-propyl ester(55943-46-9)
• EPA Substance Registry System: (S)-2-Amino-3-(3,4-dihydroxy-phenyl)-2-methyl-propionic acid 3-acetylamino-propyl ester(55943-46-9)

Safety Data

• Hazardous Substances Data: 55943-46-9(Hazardous Substances Data)

Upstream product

• 10601-73-7 N-(3-hydroxypropyl)acetamide 
• 555-30-6 methyldopa 

Relevant articles and documents

Synthesis and antihypertensive activity of some ester progenitors of methyldopa

A variety of esters of methyldopa was synthesized with the objective of obtaining derivatives that would be more efficiently absorbed from the gastrointestinal tract than the free amino acid and would undergo conversion to methyldopa readily in the blood or target tissues. Two of the esters, α-pivaloyloxyethyl and α-succinimidoethyl, were found to be more potent antihypertensive agents than methyldopa in animal models and were selected for further study in man. The amino esters were prepared by three different methods, including direct esterification of methyldopa without the use of N- or O-protecting groups.