56006-49-6

Basic information

• Product Name: (R)-ethyl-isopropyl-acetic acid
• CAS NO: 56006-49-6
• Molecular Weight: 130.187
• Mol File: 56006-49-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (R)-ethyl-isopropyl-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-ethyl-isopropyl-acetic acid(56006-49-6)
• EPA Substance Registry System: (R)-ethyl-isopropyl-acetic acid(56006-49-6)

Safety Data

• Hazardous Substances Data: 56006-49-6(Hazardous Substances Data)

Upstream product

• 84984-47-4 (+/-)-3-Ethyl-4-methyl-2-pentanone 
• 26254-92-2 α-ethylisovaleraldehyde 
• 77324-68-6 2-(1-methylethyl)-2-butenoic acid 
• 118870-82-9 (+/-)-(-1-methyl-butyl)-malonic acid 
• 67-64-1 acetone 
• 533-68-6 2-bromobutyric acid ethyl ester 
• 1735-08-6 ethyl-isopropyl-malonic acid 
• 503-74-2 3-methylbutyric acid 
• 74-96-4 ethyl bromide 
• 19780-65-5 3-ethyl-3-methyl-pentan-2-one 
• 18371-13-6 2-Methyl-2-ethyl-1-butanol 
• 75-03-6 ethyl iodide 
• 78330-46-8 Acetic acid (3S,4S,9S,10R,13R,14S,17R)-17-((S)-4-ethyl-2,3-dihydroxy-1,5-dimethyl-hexyl)-4,13,14-trimethyl-tetradecahydro-cyclopropa[9,10]cyclopenta[a]phenanthren-3-yl ester 
• 78330-46-8 Acetic acid (3S,4S,10R,13R,14S,17R)-17-((1S,4S)-4-ethyl-2,3-dihydroxy-1,5-dimethyl-hexyl)-4,13,14-trimethyl-tetradecahydro-cyclopropa[9,10]cyclopenta[a]phenanthren-3-yl ester 

Downstream Products

• 56116-35-9 2-ethyl-3-methylbutanol 
• 92372-38-8 2-ethyl-3-methyl-1-(p-tolylsulfonyloxy)butane 
• 170511-90-7 2-ethyl-3-methylbutyl phenyl sulfide 
• 170511-91-8 2-ethyl-3-methylbutyl phenyl sulphone 
• 1407870-28-3 2-ethyl-3-methyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide 

Relevant articles and documents

SYNTHESIS OF SOME NEW CHOLESTERYL ESTERS OF CHIRAL ALKANOIC ACIDS.

Six new cholesteryl esters have been prepared from chiral alkanoic acids. Oxidation of 2(S)-methylbutanol and 2(S)-ethyl-3-methybutyraldehyde gave the corresponding butyric acids, while condensation of the tosylates of the corresponding alcohols with diethyl malonate led ultimately to the substituted hexanoic acids. 2(R)-Methylpentanoic and ( minus )-2-ethylhexanoic acids were commercially available.

Synthesis and evaluation of antiallodynic and anticonvulsant activity of novel amide and urea derivatives of valproic acid analogues

Valproic acid (VPA, 1) is a major broad spectrum antiepileptic and central nervous system drug widely used to treat epilepsy, bipolar disorder, and migraine. VPA's clinical use is limited by two severe and lifethreatening side effects, teratogenicity and hepatotoxicity. A number of VPA analogues and their amide, N-methylamide and urea derivatives, were synthesized and evaluated in animal models of neuropathic pain and epilepsy. Among these, two amide and two urea derivatives of 1 showed the highest potency as antineuropathic pain compounds, with ED50 values of 49 and 51 mg/kg for the amides (19 and 20) and 49 and 74 mg/kg for the urea derivatives (29 and 33), respectively. 19, 20, and 29 were equipotent to gabapentin, a leading drug for the treatment of neuropathic pain. These data indicate strong potential for the above-mentioned novel compounds as candidates for future drug development for the treatment of neuropathic pain. 2009 American Chemical Society.

Studies on the constituents of orchidaceous plants. II. Isolation, structures, and stereochemistry of cyclonervilol, cyclohomonervilol, and dihydrocycloeucalenol C-24 epimers, new triterpenes from Nervilia purpurea Schlechter

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