56016-36-5 Usage
Description
3,3-DIMETHOXYESTR-5(10)-ENE-17BOL, a synthetic derivative of estrogen, is an estrogenic steroid with a molecular formula of C20H28O3. It features two methoxy substituents on the 3 and 3' positions of the phenolic A-ring and a double bond between the 5 and 10 positions of the steroid backbone. This chemical compound has been studied for its potential role in hormone replacement therapy and its effects on various biological systems, as well as its potential use as a therapeutic agent for conditions related to estrogen deficiency.
Uses
Used in Pharmaceutical Research:
3,3-DIMETHOXYESTR-5(10)-ENE-17BOL is used as a research compound for studying the effects of estrogenic steroids on biological systems and their potential applications in hormone replacement therapy.
Used in Hormone Replacement Therapy:
In the healthcare industry, 3,3-DIMETHOXYESTR-5(10)-ENE-17BOL is used as a potential therapeutic agent for hormone replacement therapy, aiming to alleviate symptoms and conditions related to estrogen deficiency in postmenopausal women.
Used in Therapeutic Applications for Estrogen Deficiency Conditions:
3,3-DIMETHOXYESTR-5(10)-ENE-17BOL is used as a potential treatment for conditions related to estrogen deficiency, such as osteoporosis, cardiovascular diseases, and neurodegenerative disorders, due to its estrogenic properties and effects on various biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 56016-36-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,0,1 and 6 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 56016-36:
(7*5)+(6*6)+(5*0)+(4*1)+(3*6)+(2*3)+(1*6)=105
105 % 10 = 5
So 56016-36-5 is a valid CAS Registry Number.
56016-36-5Relevant articles and documents
Novel Insertion, Rearrangement and Addition Products from Dihalogenocarbene Reactions with 5(10)-Unsaturated Steroids
Templeton, John F.,Ling, Yangzhi,Lin, Weiyang,Pitura, Randy J.,Marat, Kirk,Bridson, John N.
, p. 1149 - 1158 (2007/10/02)
Novel insertion, rearrangement and addition products from dibromocarbene and dichlorocarbene reactions with 5(10)-unsaturated steroids have been identified.The dihalogenocarbenes were prepared under phase-transfer conditions (CHBr3- or CHCl3-NaOH), and from CHBr3-KOBut-Et2O, phenyl(trichloromethyl)mercury and sodium trichloroacetate.Evidence that the major products arise from an initial dihalogenocarbene reaction on the α face of the molecule is reported.The major products obtained from addition of CBr2 to 3,17-disubstituted estr-5(10)-enes, after ketal hydrolysis, were 19(S)-bromo-9α,19-cyclo-10α-androst-4-en-3-one and 3',3',19(S)-tribromo-3'H-9α,19-cyclopropa-5β,10α-androstan-3-one derivatives together with the 19,19-dibromo-5α,19-cyclo-10α-steroid adduct.No products from addition of CBr2 to the β-face of the double bond, as previously reported, were identified.Reactions of CCl2 gave, besides rearrangement products analogous to those obtained from CBr2, a 5α-hydroxy-9α,19α-cycloandrostane derivative, the 9α-CHCl2 insertion derivative and both α- and β-face addition products to the double bond.Structures were established by homonuclear and heteronuclear correlation and nuclear Overhauser effect NMR measurements and X-ray crystallography.
