5602-94-8

Basic information

• Product Name: Methyl (etho×ycarbonyl)MethylcarbaMate
• Synonyms: Methyl (etho×ycarbonyl)MethylcarbaMate;Ethyl 2-((Methoxycarbonyl)aMino)acetate;Ethyl 2-((methoxycarbonyl)
• CAS NO: 5602-94-8
• Molecular Formula: C₆H₁₁NO₄
• Molecular Weight: 161.15584
• Mol File: 5602-94-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 247.2°C at 760 mmHg
• Flash Point: 103.3°C
• Appearance: /
• Density: 1.124g/cm³
• Vapor Pressure: 0.0261mmHg at 25°C
• Refractive Index: 1.429
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Methyl (etho×ycarbonyl)MethylcarbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl (etho×ycarbonyl)MethylcarbaMate(5602-94-8)
• EPA Substance Registry System: Methyl (etho×ycarbonyl)MethylcarbaMate(5602-94-8)

Safety Data

• Hazardous Substances Data: 5602-94-8(Hazardous Substances Data)

Usage

Uses

NSC 36233 is used in preparation of Ethylpyrrolidine Carboxylic Acids.

InChI:InChI=1/C6H11NO4/c1-3-11-5(8)4-7-6(9)10-2/h3-4H2,1-2H3,(H,7,9)

Upstream product

• 623-33-6 glycine ethyl ester hydrochloride 
• 79-22-1 methyl chloroformate 
• 67-56-1 methanol 
• 2999-46-4 Ethyl isocyanoacetate 
• 459-73-4 GlyOEt*HCl 
• 53921-04-3 methyl 3,5-dimethyl-1H-pyrazole-1-carboxylate 
• 186581-53-3 diazomethane 
• 75-44-5 phosgene 

Downstream Products

• 1670-97-9 N-(methoxycarbonyl)glycine 
• 921930-88-3 methyl N-(2-hydroxy-2,2-diphenylethyl)carbamate 

Relevant articles and documents

Preparation method and application of (3R, 4S)-4-ethylpyrrolidine-3-carboxylic acid compound

The embodiment of the invention discloses a preparation method and application of a (3R, 4S)-4-ethylpyrrolidine-3-carboxylic acid compound, and relates to the technical field of drug synthesis. The (3R, 4S)-4-ethylpyrrolidine-3-carboxylic acid is synthesized by taking glycine ethyl ester as a raw material and sequentially carrying out amino protecting group addition, ring closing, substitution, coupling, catalytic hydrogenation, hydrolysis and protecting group removal. The target product synthesized by the reaction has high yield and chiral purity, and also has the advantages of simple and accessible raw materials, simple synthesis route, mild reaction conditions, simple separation and purification operation and low synthesis cost.

New facile alkoxycarbonylating agent, alkyl pyrazole-1-carboxylates. The preparation and the utilities

Alkyl pyrazole-1-carboxylates (2), which were readily prepared from alkyl chloroformate or carbazate in good yields, were provided as the new facile alkoxycarbonylating agents toward the Grignard reagents for the synthesis of one carbon higher carboxylic esters. Also amines were alkoxycarbonylated by 2 to produce the corresponding urethanes even in an aqueous medium. Benzyl 3,5-dimethylpyrazole-1-carboxylate (2d) could be utilized for the Cbz-protection of amino acids and esters in good yield without any racemization.

Total synthesis of (±)-7-Epi-20-desethylgelsedine

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