5603-22-5

Basic information

• Product Name: 8-Hydroxy-2-quinolinecarbaldehyde oxime
• Synonyms: 8-Hydroxy-2-quinolinecarbaldehyde oxime;8-Hydroxyquinoline-2-carbaldehyde oxiMe
• CAS NO: 5603-22-5
• Molecular Formula: C10H8N2O2
• Molecular Weight: 188.19
• Mol File: 5603-22-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: 172-173 °C
• Boiling Point: 410.7±25.0 °C(Predicted)
• Appearance: /
• Density: 1.33±0.1 g/cm3(Predicted)
• PKA: 9.13±0.30(Predicted)
• CAS DataBase Reference: 8-Hydroxy-2-quinolinecarbaldehyde oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Hydroxy-2-quinolinecarbaldehyde oxime(5603-22-5)
• EPA Substance Registry System: 8-Hydroxy-2-quinolinecarbaldehyde oxime(5603-22-5)

Safety Data

• Hazardous Substances Data: 5603-22-5(Hazardous Substances Data)

Usage

Chemical compound

8-Hydroxy-2-quinolinecarbaldehyde oxime

Also known as

Quinaldicarbamine

Derived from

8-hydroxyquinoline

Properties

Chelating properties in extraction and separation of metal ions

Uses

Reagent in analytical chemistry, complexing agent in synthesis of coordination compounds

Potential applications

Treatment of human and animal diseases, development of new materials

Upstream product

• 14510-06-6 2-formyl oxine 

Downstream Products

• 17018-81-4 2-aminomethyl-8-hydroxyquinoline 

Relevant articles and documents

S-shaped decanuclear heterometallic [Ni8Ln2] complexes [Ln(iii) = Gd, Tb, Dy and Ho]: Theoretical modeling of the magnetic properties of the gadolinium analogue

The reaction of 8-quinolinol-2-carboaldoxime (LH2) with Ni II and LnIII salts afforded the heterometallic decanuclear compounds [Ni8Dy2(μ3-OH) 2(L)8(LH)2(H2O)6] (ClO4)2·16H2O (1), [Ni 8Gd2(μ3-OH)2(L) 8(LH)2(H2O)4(MeOH) 2](NO3)2·12H2O (2), [Ni 8Ho2(μ3-OH)2(L) 8(LH)2(H2O)4(MeOH) 2](ClO4)2·2MeOH·12H2O (3) and [Ni8Tb2 (μ3-OH)2(L) 8(LH)2(MeOH)4(OMe)2]·2CH 2Cl2·8H2O (4). While compounds 1-3 are dicationic, compound 4 is neutral. These compounds possess an S-shaped architecture and comprise a long chain of metal ions bound to each other. In all the complexes, the eight NiII and two LnIII ions of the multimetallic ensemble are hold together by two μ3-OH, eight dianionic (L2-) and two monoanionic oxime ligands (LH-) whereas compound 4 has two μ3-OH, eight dianionic (L 2-), two monoanionic oxime ligands (LH-) and two terminal methoxy (MeO-) ligands. The central portion of the S-shaped molecular wire is made up of an octanuclear NiII ensemble which has at its two ends the LnIII caps. Magnetic studies on 1-4 reveal that the magnetic interactions between neighboring metal ions are negligible at room temperature. On the other hand, at lower temperatures in all the compounds anti-ferromagnetic interactions seem to be dominated. Analysis of the magnetic data for the GdIII derivative indicates NiII-Ni II anti-ferromagnetic interactions and GdIII-Ni II ferromagnetic interactions at low temperatures. A theoretical density functional study on the magnetic behavior of the GdIII derivative suggests that while the weak ferromagnetic interaction between GdIII and NiII is in line with the expectation of the magnetic interactions between orthogonal d and f orbitals, antiferromagnetic NiII-NiII interactions are related to the wide Ni-O-Ni angles (～102°) and quasi-planar conformation of the Ni2O 2 core.