56051-09-3

Basic information

• Product Name: Benzenemethanol, a-[(methylseleno)methyl]-
• CAS NO: 56051-09-3
• Molecular Formula: C9H12OSe
• Molecular Weight: 215.154
• Mol File: 56051-09-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-[(methylseleno)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-[(methylseleno)methyl]-(56051-09-3)
• EPA Substance Registry System: Benzenemethanol, a-[(methylseleno)methyl]-(56051-09-3)

Safety Data

• Hazardous Substances Data: 56051-09-3(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 7101-31-7 dimethyl diselenide 
• 56051-03-7 bis(methylseleno)-methane 
• 100-52-7 benzaldehyde 
• 96-09-3 styrene oxide 

Downstream Products

• 56268-17-8 (RS)-O-acetyl-1-phenyl-2-(methylseleno) ethanol 

Relevant articles and documents

Iodosobenzene-Mediated Three-Component Selenofunctionalization of Olefins

A three-component reaction of olefin, diselenide and water, alcohols, phenol, carboxylic acid, or amine by a commercially available hypervalent iodine(III) reagent, PhIO, was developed. This method provides access to a wide range of vicinally functionalized selenoderivatives under ambient conditions with mostly excellent yields and high diastereoselectivity. The developed reaction displays high levels of functional group compatibility and is suitable for the late-stage functionalization of styrene-functionalized biomolecules. Preliminary investigations on the mechanism of the reaction are also presented.

Efficient Protocol for Synthesis of β-Hydroxy(alkoxy)selenides via Electrochemical Iodide-Catalyzed Oxyselenation of Styrene Derivatives with Dialkyl(aryl)diselenides

An efficient protocol for the synthesis of β-hydroxy(alkoxy)selenides was developed through the electrochemical iodide-catalyzed oxyselenation of styrene derivatives with dialkyl(aryl)diselenides under mild reaction conditions. Mechanistic studies showed that the cation I+ is involved during the whole process, and accelerates the formation of seleniranium ion via substitution and addition reaction with dialkyl(aryl)diselenides and styrene derivatives. The corresponding products are formed in good to excellent yields. This electrochemical oxyselenation provides an efficient strategy for difunctionalization of alkenes.

UNUSUAL REACTIVITY OF SELENOBORANES TOWARDS EPOXIDES: NEW SELECTIVE ROUTES TO β-HYDROXYSELENIDES AND ALLYLALCOHOLS

Selenoboranes react with terminal, α, β- di- and trisubstituted epoxides to produce β-hydroxyselenides (or olefins) in the two first cases and allyl alcohols in the last one.A very high stereodescrimination has been observed for α,β-disubstituted epoxides: the cis epoxide being much more reactive.