561066-93-1

Basic information

• Product Name: Heptanoic acid, 3-amino-2-hydroxy-
• Synonyms: Heptanoic acid, 3-amino-2-hydroxy-;3-Amino-2-hydroxyheptanoic acid
• CAS NO: 561066-93-1
• Molecular Formula: C₇H₁₅NO₃
• Molecular Weight: 161.2
• Mol File: 561066-93-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 345.1±27.0 °C(Predicted)
• Appearance: /
• Density: 1.146±0.06 g/cm3(Predicted)
• PKA: 3.04±0.32(Predicted)
• CAS DataBase Reference: Heptanoic acid, 3-amino-2-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Heptanoic acid, 3-amino-2-hydroxy-(561066-93-1)
• EPA Substance Registry System: Heptanoic acid, 3-amino-2-hydroxy-(561066-93-1)

Safety Data

• Hazardous Substances Data: 561066-93-1(Hazardous Substances Data)

Usage

General Description

Heptanoic acid, 3-amino-2-hydroxy- is a chemical compound that consists of a heptanoic acid molecule attached to an amino and hydroxy groups. It is also known as 3-amino-2-hydroxyheptanoic acid or omega-amino-omega-hydroxy caprylic acid. Heptanoic acid, 3-amino-2-hydroxy- is commonly used as a precursor in the synthesis of various pharmaceuticals and is also used as a chiral resolving agent in chromatography. In addition, heptanoic acid, 3-amino-2-hydroxy- has potential applications in the food and cosmetic industries due to its antimicrobial and antioxidant properties. Overall, this chemical compound has a variety of industrial and research applications due to its unique chemical structure and properties.

Upstream product

• 561066-92-0 3-nitro-2-hydroxyheptanoic acid 
• 628-05-7 1-nitropentane 

Downstream Products

• 367258-50-2 {1-[({[(dimethylcarbamoyl-phenyl-methyl)-carbamoyl]-methyl}-carbamoyl)-hydroxy-methyl]-pentyl}-carbamic acid tert-butyl ester 
• 561067-01-4 N-(1-carbamoyl-1-hydroxyhex-1-yl)-2-[E-2-(4-dimethylaminomethylphenyl)ethen-1-yl]benzamide 

Relevant articles and documents

Discovery of SCH446211 (SCH6): A new ketoamide inhibitor of the HCV NS3 serine protease and HCV subgenomic RNA replication

Introduction of various modified prolines at P2 and optimization of the P1 side chain led to the discovery of SCH6 (24, Table 2), a potent ketoamide inhibitor of the HCV NS3 serine protease. In addition to excellent enzyme potency (Ki* = 3.8 nM), 24 was also found to be a potent inhibitor of HCV subgenomic RNA replication with IC50 and IC90 of 40 and 100 nM, respectively. Recently, antiviral activity of 24 was demonstrated with inhibition of the full-length genotype 2a HCV genome. In addition, 24 was found to restore the responsiveness of the interferon regulatory factor 3 (IRF-3) in cells containing HCV RNA replicons.