56159-20-7

Basic information

• Product Name: 3-methoxycarbonyl-2-phenylfuro<3,2-c>pyridine
• CAS NO: 56159-20-7
• Molecular Weight: 253.257
• Mol File: 56159-20-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methoxycarbonyl-2-phenylfuro<3,2-c>pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methoxycarbonyl-2-phenylfuro<3,2-c>pyridine(56159-20-7)
• EPA Substance Registry System: 3-methoxycarbonyl-2-phenylfuro<3,2-c>pyridine(56159-20-7)

Safety Data

• Hazardous Substances Data: 56159-20-7(Hazardous Substances Data)

Upstream product

• 1122-96-9 4-methoxypyridine N-oxide 
• 4891-38-7 phenylpropynoic acid methyl ester 
• 1121-76-2 4-chloropyridine N-oxide 

Relevant articles and documents

THE REACTION OF 4-CHLOROPYRIDINE 1-OXIDES WITH ACTIVATED ACETYLENES. A CONVENIENT ONE-STEP SYNTHESIS OF FUROPYRIDINES

The reaction of 4-chloro- and 4-pseudohalogeno-pyridine 1-oxides with activated acetylenes (phenylcyanoacetylene, methyl phenylpropiolate, phenylpropiolaldehyde, methyl propiolate, and ethynyl p-tolyl sulphone) gave good yields of substituted furopyridines 7.With 1-phenyl-2-methanesulphonylacetylene under mild conditions the initial -shift product 9 was isolated and converted to 7 with base.The structure of 7 was established unambiguously by using Eu(fod)3-induced NMR shifts.The mechanism of the reaction is discussed briefly and consecutive -shifts are proposed to account for the formation 7.