562098-74-2Relevant articles and documents
Utilization of a β-aminophosphotyrosyl mimetic in the design and synthesis of macrocyclic Grb2 SH2 domain-binding peptides
Lee, Kyeong,Zhang, Manchao,Liu, Hongpeng,Yang, Dajun,Burke Jr., Terrence R.
, p. 2621 - 2630 (2007/10/03)
Grb2 SH2 domains are protein-docking modules that exert important functions in both normal and pathogenic signal transduction processes. Development of synthetic Grb2 SH2 domain binding ligands is being pursued by several groups as potential new therapies