5621-17-0

Basic information

• Product Name: 4,7-DIMETHYLINDOLE
• Synonyms: 4,7-DIMETHYLINDOLE;1H-Indole, 4,7-diMethyl-;4,7-DiMethyl-1H-indole
• CAS NO: 5621-17-0
• Molecular Formula: C₁₀H₁₁N
• Molecular Weight: 145.20104
• Mol File: 5621-17-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 102 °C
• Boiling Point: 275.7±9.0 °C(Predicted)
• Appearance: /
• Density: 1.080±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 17.66±0.30(Predicted)
• CAS DataBase Reference: 4,7-DIMETHYLINDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,7-DIMETHYLINDOLE(5621-17-0)
• EPA Substance Registry System: 4,7-DIMETHYLINDOLE(5621-17-0)

Safety Data

• Hazardous Substances Data: 5621-17-0(Hazardous Substances Data)

Usage

General Description

4,7-Dimethylindole is a chemical compound with the molecular formula C10H11N. It is a pale yellow to brownish solid that is insoluble in water but soluble in organic solvents. It is commonly used as a building block in the synthesis of pharmaceuticals, dyes, and other organic compounds. 4,7-Dimethylindole has been studied for its potential as a fluorescent dye and as a precursor for the production of indole-based drugs and materials. It is also known to have potential toxic effects on the environment and human health, and thus must be handled and disposed of with caution. Overall, 4,7-Dimethylindole is a versatile and important compound in organic chemistry with various potential applications in the pharmaceutical and chemical industries.

InChI:InChI=1S/C10H11N/c1-7-3-4-8(2)10-9(7)5-6-11-10/h3-6,11H,1-2H3

Upstream product

• 95-78-3 2,5-Dimethylaniline 
• 107-21-1 ethylene glycol 

Downstream Products

• 20355-42-4 1,4,5,8-Tetramethyl-carbazol 

Relevant articles and documents

β-Amino alcohols from anilines and ethylene glycol through heterogeneous Borrowing Hydrogen reaction

Borrowing Hydrogen (BH), also called Hydrogen Autotransfer (HA), reaction with neat ethylene glycol represents a key step in the preparation of β-amino alcohols. However, due to the stability of ethylene glycol, mono-activation has rarely been achieved. Herein, a combination of Pd/C and ZnO is reported as heterogeneous catalyst for this BH/HA reaction. This system results in an extremely air and moisture stable, and economic catalyst able to mono-functionalize ethylene glycol in water, without further activation of the diol. In this work, different diols and aromatic amines have been explored affording a new approach towards amino alcohols. This study reveals how the combination of two solid species can afford interesting catalytic properties in heterogeneous phase. ZnO activates ethylene glycol while Pd/C is the responsible of the BH/HA cycle. This catalytic system has also been found useful to dehydrogenate indoles affording indolines that undergo in situ BH/HA cycle prior to re-aromatization, representing a tandem heterogeneous process.