5622-38-8 Usage
General Description
Ethyl 2-(quinolin-6-yl)acetate is a chemical compound that is a member of the quinoline family, which are nitrogen-containing compounds that are widely used in medicinal chemistry. The structure of ethyl 2-(quinolin-6-yl)acetate comprises a quinoline ring attached to an acetate group, with an ethyl group attached to the acetate. ETHYL 2-(QUINOLIN-6-YL)ACETATE is soluble in many common organic solvents. It does not appear to have significant applications in industry or commerce, but may be used in scientific research settings, particularly in the context of exploring the properties and reactions of similar chemical structures. As with many chemicals of this type, it should be handled with care to avoid potential health risks associated with exposure.
Check Digit Verification of cas no
The CAS Registry Mumber 5622-38-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,2 and 2 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5622-38:
(6*5)+(5*6)+(4*2)+(3*2)+(2*3)+(1*8)=88
88 % 10 = 8
So 5622-38-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H13NO2/c1-2-16-13(15)9-10-5-6-12-11(8-10)4-3-7-14-12/h3-8H,2,9H2,1H3
5622-38-8Relevant articles and documents
Copper-Catalyzed Ullmann-Type Coupling and Decarboxylation Cascade of Arylhalides with Malonates to Access α-Aryl Esters
Cheng, Fei,Chen, Tao,Huang, Yin-Qiu,Li, Jia-Wei,Zhou, Chen,Xiao, Xiao,Chen, Fen-Er
supporting information, p. 115 - 120 (2022/01/04)
We have developed a high-efficiency and practical Cu-catalyzed cross-coupling to directly construct versatile α-aryl-esters by utilizing readily available aryl bromides (or chlorides) and malonates. These gram-scale approaches occur with turnovers of up to 1560 and are smoothly conducted by the usage of a low catalyst loading, a new available ligand, and a green solvent. A variety of functional groups are tolerated, and the application occurs with α-aryl-esters to access nonsteroidal anti-inflammatory drugs (NSAIDs) on the gram scale.
