5622-76-4

Basic information

• Product Name: Benzene,1-buten-3-ynyl-
• CAS NO: 5622-76-4
• Molecular Weight: 128.174
• Mol File: 5622-76-4.mol
• Article Data: 61

Chemical Properties

• CAS DataBase Reference: Benzene,1-buten-3-ynyl- (CAS DataBase Reference)
• NIST Chemistry Reference: Benzene,1-buten-3-ynyl- (5622-76-4)
• EPA Substance Registry System: Benzene,1-buten-3-ynyl- (5622-76-4)

Safety Data

• Hazardous Substances Data: 5622-76-4(Hazardous Substances Data)

Upstream product

• 56772-77-1 1-phenyl-4,4-dichloro-1,3-butadiene 
• 77150-87-9 (Z)-1-(4-bromobuta-1,3-dienyl)benzene 
• 80605-26-1 4-bromo-4-phenyl-1-butyne 
• 935-01-3 (Z)-1-phenylbuten-3-yne 
• 275-51-4 azulene 
• 14371-10-9 (E)-3-phenylpropenal 
• 84645-45-4 lithio(trimethylsilyl)diazomethane 
• 38002-48-1 E/Z-(4-phenylbut-3-ene-1-inyl)trimethyl-silane 
• 405516-51-0 (E)-1-chloro-4-phenyl-1-(phenylsulfinyl)but-3-ene-2-ol 
• 152236-07-2 1-chloro-4-phenyl-1-phenylsulfinyl-1,3-butadiene 
• 39598-55-5 (bromomethylene)triphenylphosphorane 
• 104-55-2 3-phenyl-propenal 
• 100-52-7 benzaldehyde 
• 135217-63-9 (3-trimethylsilanyl-prop-2-ynyl)-phosphonic acid diethyl ester 

Downstream Products

• 91-20-3 naphthalene 
• 275-51-4 azulene 
• 928-90-5 5-hexyl-1-ol 
• 1072110-51-0 (E)-10-phenyldec-9-ene-5,7-diyn-1-yl N-phenylcarbamate 
• 122059-63-6 2-((E)-Styryl)-4,5,6,7-tetrahydro-3aH-isoxazolo[2,3-a]pyridine 

Relevant articles and documents

Selective Rhodium-Catalyzed Hydroformylation of Terminal Arylalkynes and Conjugated Enynes to (Poly)enals Enabled by a π-Acceptor Biphosphoramidite Ligand

The hydroformylation of terminal arylalkynes and enynes offers a straightforward synthetic route to the valuable (poly)enals. However, the hydroformylation of terminal alkynes has remained a long-standing challenge. Herein, an efficient and selective Rh-catalyzed hydroformylation of terminal arylalkynes and conjugated enynes has been achieved by using a new stable biphosphoramidite ligand with strong π-acceptor capacity, which affords various important E-(poly)enals in good yields with excellent chemo- and regioselectivity at low temperatures and low syngas pressures.

Aminium cation-radical catalysed selective hydration of (E)-aryl enynes

The hydration of carbon-carbon triple bonds is an important and atom economic synthetic transformation. Herein, we report a mild and selective method for the catalytic Markovnikov hydration of (E)-aryl enynes to the corresponding enones, mediated through the bench-stable aminium salt, tris(4-bromophenyl)ammoniumyl hexachloroantimonate (TBPA). The chemoselective and diastereoselective method proceeds under neutral metal-free conditions, delivering excellent product yields from terminal and internal alkyne units. The synthesis of biologically important (E)-3-styrylisocoumarins, including a formal synthesis of the natural product achlisocoumarin III, demonstrates the utility of this novel transformation.

Iron-Catalyzed Tertiary Alkylation of Terminal Alkynes with 1,3-Diesters via a Functionalized Alkyl Radical

Direct oxidative C(sp)?H/C(sp3)?H cross-coupling offers an ideal and environmentally benign protocol for C(sp)?C(sp3) bond formations. As such, reactivity and site-selectivity with respect to C(sp3)?H bond cleavage have remained a persistent challenge. Herein is reported a simple method for iron-catalyzed/silver-mediated tertiary alkylation of terminal alkynes with readily available and versatile 1,3-dicarbonyl compounds. The reaction is suitable for an array of substrates and proceeds in a highly selective manner even employing alkanes containing other tertiary, benzylic, and C(sp3)?H bonds alpha to heteroatoms. Elaboration of the products enables the synthesis of a series of versatile building blocks. Control experiments implicate the in situ generation of a tertiary carbon-centered radical species.