56233-10-4

Basic information

• Product Name: N-(2-phenylethyl)-N'-methylpiperazine
• Synonyms: N-(2-phenylethyl)-N'-methylpiperazine
• CAS NO: 56233-10-4
• Molecular Weight: 204.315
• Mol File: 56233-10-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: N-(2-phenylethyl)-N'-methylpiperazine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-phenylethyl)-N'-methylpiperazine(56233-10-4)
• EPA Substance Registry System: N-(2-phenylethyl)-N'-methylpiperazine(56233-10-4)

Safety Data

• Hazardous Substances Data: 56233-10-4(Hazardous Substances Data)

Upstream product

• 109-01-3 1-methyl-piperazine 
• 1015484-22-6 1-methyl-4-((trifluoro-λ⁴-boranyl)methyl)piperazine potassium 
• 100-44-7 benzyl chloride 
• 100-42-5 styrene 
• 103-63-9 1-phenyl-2-bromoethane 
• 55-86-7 mechlorethamine hydrochloride 
• 140-29-4 phenylacetonitrile 

Relevant articles and documents

A potassium magnesiate complex: Synthesis, structure and catalytic intermolecular hydroamination of styrenes

A new heterobimetallic potassium magnesiate complex KMg[N(SiMe3)2]2Bn (Bn = PhCH2-) was synthesized by simply mixing magnesium amide and potassium benzyl in toluene. The TMEDA-ligated potassium magnesiate comple

Lithium-Catalyzed anti-Markovnikov Intermolecular Hydroamination Reactions of Vinylarenes and Simple Secondary Amines

Various β-arylethylamine derivatives were straightforwardly obtained by the lithium-catalyzed anti-Markovnikov selective intermolecular hydroamination reaction of secondary aliphatic amines with vinylarenes. The use of only 1.5 mol % LiCH2TMS as a solid base in THF proved to be efficient to deliver the target products at room temperature with up to complete conversions. Both reaction partners were, moreover, used in equivalent amounts; thus, this protocol best respects the concepts of sustainable chemistry for the easy preparation of lead structures for pharmaceutically active compounds.

Synthesis of β-phenylethylamines from styrene derivatives

β-Phenylethylamines are prepared from the styrene derivatives; 4,4- dimethyl-2-(2-vinylphenyl)-2-oxazoline, 2-(3-methoxy-2-vinylpnenyl)-4,4- dimethyl-2-oxazoline, 2-vinylbenzoic acid, styrene, β-methylstyrene, and α- methylstyrene.