56239-22-6Relevant articles and documents
Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase
Tomasic, Tihomir,Zidar, Nace,Rupnik, Veronika,Kovac, Andreja,Blanot, Didier,Gobec, Stanislav,Kikelj, Danijel,Masic, Lucija Peterlin
scheme or table, p. 153 - 157 (2009/05/07)
Mur ligases catalyze the biosynthesis of the UDP-MurNAc-pentapeptide precursor of peptidoglycan, an essential polymer of bacterial cell-wall. They constitute attractive targets for the development of novel antibacterial agents. Here we report on the synth