5627-11-2

Basic information

• Product Name: Hydroxylamine,O,O'-1,2-ethanediylbis-
• CAS NO: 5627-11-2
• Molecular Weight: 92.0977
• Mol File: 5627-11-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Hydroxylamine,O,O'-1,2-ethanediylbis- (CAS DataBase Reference)
• NIST Chemistry Reference: Hydroxylamine,O,O'-1,2-ethanediylbis- (5627-11-2)
• EPA Substance Registry System: Hydroxylamine,O,O'-1,2-ethanediylbis- (5627-11-2)

Safety Data

• Hazardous Substances Data: 5627-11-2(Hazardous Substances Data)

Usage

General Description

Hydroxylamine, O,O'-1,2-ethanediylbis- is a chemical compound with the formula (HO)2NCH2CH2NHOH. It is a powerful reducing agent and is commonly used in the synthesis of pharmaceuticals, pesticides, and other organic compounds. It is also used as an intermediate in the production of other chemicals, such as hydroxylamine-O-sulfonic acid. Hydroxylamine,O,O'-1,2-ethanediylbis- is highly reactive and must be handled with caution, as it can react violently with oxidizing agents and should be stored in a cool, dry place away from light and heat sources. Additionally, hydroxylamine, O,O'-1,2-ethanediylbis- poses health hazards and can cause irritation to the skin, eyes, and respiratory system, therefore proper safety measures should be taken when handling this chemical.

Upstream product

• 92670-17-2 N,N'-diisopropyl-1,2-bis(aminooxy)ethane 
• 557-30-2 glyoxime 

Downstream Products

• 1107064-58-3 5-methoxy-6'-hydroxy-2,2'-[ethylenedioxybis(nitrilomethylidyne)]diphenol 
• 1371631-40-1 3-ethoxysalicylaldehyde-O-(1-ethyloxyamide)oxime 
• 1544717-05-6 C₃₆H₃₂N₆O₄ 
• 209115-54-8 1,2-bis[N,N'-(2-mesitylsulphonyl)aminooxy]ethane 
• 103860-60-2 2,3‐dihydroxynaphthalene‐1,4‐dicarbaldehyde 
• 1370040-70-2 2-hydroxy-3,5-dibromobenzaldehyde-O-(2-(aminooxy)ethyl)oxime 
• 1493774-01-8 6,6'-diethoxy-2,2'-[1,1'-(ethylenedioxydinitrilo)dimethylidyne]diphenol 

Relevant articles and documents

Oxidation of N,N'-Dialkyl-1,2-bishydroxylamines

Oxidation of N,N'-dialkyl-1,2-bishydroxylamines RNHOCH2CH2ONHR gives products that are a function of oxidant.For R = i-Pr (5) and m-chloroperbenzoic acid the products are diisopropyl azo dioxide, HOCH2CH2ONHCH(CH3)2, and ethylene glycol.Product ratios indicate independent oxidation of the two hydroxylamine functions.Na2WO4/H2O2 in D2O gives the azo dioxide, ethylene glycol, and acetone oxime.Oxidation with bromine and 1,4-diazabicyclooctane or tert-butyl hypochlorite and triethylamine gives product ratios that are consistent with two pathways to the bis oxime 7: one that appears to give 7 directly and a second that goes through the monohydroxylamine monooxime 15.It is proposed that the former reaction proceeds through the 1,4,2,3-dioxadiazine ring, which is oxidized quickly to products.Reaction products from the bishydroxylamine with R = CH3 are similar to those with R = i-Pr.