56271-34-2

Basic information

• Product Name: N-(p-toluenesulfonyl)-d,l-alanyl chloride
• Synonyms: N-(p-toluenesulfonyl)-d,l-alanyl chloride
• CAS NO: 56271-34-2
• Molecular Weight: 261.729
• Mol File: 56271-34-2.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: N-(p-toluenesulfonyl)-d,l-alanyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: N-(p-toluenesulfonyl)-d,l-alanyl chloride(56271-34-2)
• EPA Substance Registry System: N-(p-toluenesulfonyl)-d,l-alanyl chloride(56271-34-2)

Safety Data

• Hazardous Substances Data: 56271-34-2(Hazardous Substances Data)

Upstream product

• 4816-81-3 p-tosyl-L-alanine 
• 98-59-9 p-toluenesulfonyl chloride 
• 79-37-8 oxalyl dichloride 
• 21957-58-4 N-(p-toluenesulfonyl)-DL-alanine 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 122081-14-5 4-Methyl-N-(1-methyl-2-oxo-2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide 
• 1041196-15-9 C₁₅H₂₂N₂O₃S 
• 1093379-07-7 C₁₅H₂₃NO₄S 
• 1093379-11-3 C₁₄H₂₁NO₄S 
• 1024732-27-1 N-(1-methyl-2-oxo-2-(p-chloroanilino)ethyl)-p-toluenesulphonamide 
• 1041183-70-3 N-(1-methyl-2-oxo-2-(p-nitroanilino)ethyl)-p-toluenesulphonamide 
• 1093379-22-6 N-(1,3-dimethyl-2-oxo-3-azabutanyl)-p-toluenesulphonamide 
• 374622-08-9 N-(1-methyl-2-oxo-3-aza-3-ethylpentanyl)-p-toluenesulphonamide 
• 101289-30-9 N-(1-methyl-2-oxo-2-anilinoethyl)-p-toluenesulphonamide 
• 60522-12-5 C₁₃H₁₉NO₄S 
• 1093379-35-1 N-(1-methyl-2-oxo-2-(N-methylanilino)ethyl)-p-toluenesulphonamide 
• 69320-91-8 2-(Toluene-4-sulfonylamino)-propionic acid tert-butyl ester 
• 1438048-05-5 C₁₈H₂₂N₂O₃S 
• 331000-11-4 (2S,3S)-2-Methyl-3-phenyl-1-(toluene-4-sulfonyl)-azetidin-3-ol 

Relevant articles and documents

Iodine-Catalyzed Synthesis of Chiral 4-Imidazolidinones Using α-Amino Acid Derivatives via Dehydrogenative N-H/C(sp3)-H Coupling

An efficient method for the asymmetric synthesis of 4-imidazolidinones via an iodine-catalyzed intramolecular N-H/C(sp3)-H activation of readily available and abundant feedstocks, amino acids, and amines is described. The reaction proceeded under visible light irradiation to afford a variety of 4-imidazolidinone derivatives under mild conditions in moderate to excellent yields. Secondary and tertiary C(sp3)-H bonds were aminated, and various functional groups were tolerated.

Palladium-Catalyzed Modular Synthesis of Substituted Piperazines and Related Nitrogen Heterocycles

We report here a novel method for the modular synthesis of highly substituted piperazines and related bis-nitrogen heterocycles via a palladium-catalyzed cyclization reaction. The process couples two of the carbons of a propargyl unit with various diamine components to provide nitrogen heterocycles in generally good to excellent yields and high regio- and stereochemical control. (Chemical Equation Presented).

1,5-rhodium shift in rearrangement of N -arenesulfonylazetidin-3-ols into benzosultams

Benzosultams are synthesized in an enantiopure form starting from α-amino acids through a rhodium-catalyzed rearrangement reaction of N-arenesulfonylazetidin-3-ols. Mechanistically, this reaction involves C-C bond cleavage by β-carbon elimination and C-H bond cleavage by a 1,5-rhodium shift.